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Title Mitochondria and cell death / organized and edited by G.C. Brown, D.G. Nicholls and C.E. Cooper
Published London : Portland Press, [1999]


Location Call no. Vol. Availability
 MELB  571.65736 Bro/Mac  AVAILABLE
Description x, 225 pages : illustrations ; 26 cm
Series Biochemical Society symposium, 0067-8964 ; no. 66
Biochemical Society (Great Britain). Symposium. Biochemical Society symposia ; no. 66
Contents 1. Mitochondrial control of apoptosis: an overview / G. Kroemer -- 2. Nitric oxide, cytochrome c and mitochondria / G. C. Brown and V. Borutaite -- 3. Ceramide induces cytochrome c release from isolated mitochondria / C. Richter and P. Ghafourifar -- 4. Bcl-2 and Ca[superscript 2+]-mediated mitochondrial dysfunction in neural cell death / A. N. Murphy and G. Fiskum -- 5. Mitochondria, NO and neurodegeneration / M. F. Beal -- 6. Excitotoxicity and mitochondria / D. G. Nicholls, S. L. Budd and M. W. Ward / [et al.] -- 7. Apoptosis and necrosis: different execution of the same death / P. Nicotera, M. Leist and E. Ferrando-May -- 8. The mitochondrial permeability transition: the brain's point of view / J. M. Dubinsky, N. Brustovetsky and V. Pinelis / [et al.] -- 9. Mitochondrial dysfunction in Parkinson's disease / J. T. Greenamyre, G. MacKenzie and T.-I. Peng / [et al.] -- 10. Secondary abnormalities of mitochondrial DNA associated with neurodegeneration / S. J. Tabrizi and A. H. V. Schapira -- 11. Mutations of the mitochondrial genome: clinical overview and possible pathophysiology of cell damage / S. M. Rothman -- 12. In vivo measurements of mitochondrial function and cell death following hypoxic/ischaemic damage to the new-born brain / C. E. Cooper -- 13. Mitochondria in heart ischaemia and aging / R. G. Hansford, N. Tsuchiya and S. Pepe -- 14. Mitochondrial dysfunction in sepsis / M. Singer and D. Brealey -- 15. The mitochondrial permeability transition pore / M. Crompton, S. Virji and V. Doyle / [et al.] -- 16. The mitochondrial permeability transition: its molecular mechanism and role in reperfusion injury / A. P. Halestrap -- 17. Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death / J. J. Lemasters, T. Qian and L. C. Trost / [et al.]
Summary "This book reviews the role of mitochondria in cell death and disease through a series of chapters which present the latest research and thinking on the subject from some of the key researchers in the field. Several different lines of research have converged on the mitochondrion and its role in cell death, including mitochondrial permeability transition, apoptosis, neurodegeneration and excitotoxicity, mitochondrial DNA diseases, free radicals and nitric oxide and hypoxia/ischaemia. This volume will help to unravel these complex multiple interactions, as well as to stimulate further breakthroughs in this exciting field. It contains essential reading for researchers and postgraduates in all areas of biology and medical science."--BOOK JACKET
Notes Includes index
Bibliography Includes bibliographical references and index
Notes Also available via the World Wide Web
System requirements: Internet connectivity, World Wide Web browser, and Adobe Acrobat reader
Biochemical Society symposium no:66 0067-8694
Subject Cell death -- Congresses.
Cell death.
Mitochondria -- Congresses.
Genre/Form Conference papers and proceedings.
Author Brown, Guy C.
Cooper, Chris E.
Nicholls, David G.
Biochemical Society (Great Britain). Symposium (66th : 1998 : Sheffield, Eng.)
ISBN 1855781255