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Author Topaz, On, author

Title Cardiovascular Thrombus : From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions / On Topaz
Published [Place of publication not identified] : Elsevier Ltd. : Academic Press, 2018
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Description 1 online resource
Contents Front Cover; Cardiovascular Thrombus; Cardiovascular Thrombus; Copyright; Dedication; Contents; List of Contributors; Foreword; Preface; 1 -- Histopathology of Cardiovascular Thrombus; PREVALENCE OF HEART DISEASE; CORONARY THROMBOSIS: INCIDENCE AND ETIOLOGY; Plaque Rupture; NECROTIC CORE EXPANSION (PLAQUE FISSURE AND INTRAPLAQUE HEMORRHAGE); Erosion; Calcified Nodule; Healed Plaque Rupture; CONCLUSION; REFERENCES; 2 -- Pathology of Arterial Thrombosis: Characteristics and Thrombus Types; INTRODUCTION; ATHEROSCLEROSIS; TYPES OF THROMBI DURING ACUTE MYOCARDIAL INFARCTION
Coagulation Under Flow: Zero-Dimensional ModelsCoagulation and Biophysical Factors: Two- and Three-Dimensional Models; Blood as an Excitable Medium; Size Thresholds; Advection-Reaction-Diffusion Models and Spatial Heterogeneity; MODELS OF FIBRIN POLYMERIZATION; MODELS OF FIBRINOLYSIS; SUMMARY; ACKNOWLEDGMENTS; REFERENCES; 6 -- Animal Models of Thrombosis; BRIEF OVERVIEW OF THE PATHOGENESIS OF THE THROMBOTIC PROCESS; DEVELOPMENT OF ANIMAL MODELS OF THROMBOSIS; SMALL ANIMAL MODELS OF THROMBOSIS: THE MURINE MODELS; LARGE ANIMAL MODELS OF THROMBOSIS; Canine Models of Thrombosis
METHODS TO DETECT THROMBIRISK FACTORS FOR ARTERIAL AND VENOUS THROMBOSIS; ATHEROSCLEROSIS, INFLAMMATION, AND THROMBOSIS; TREATMENT OF ATHERO-CRYSTALLOIDS; TREATMENT OF ARTERIAL THROMBOSIS; FIBRINOLYSIS; CLOT RETRACTION AND FIBRINOLYSIS; REFERENCES; 3 -- Fibrin Clot Structure and Function: A Novel Risk Factor for Arterial and Venous Thrombosis and Thromboembolism; INTRODUCTION; FIBRIN AND CLOT FORMATION; FACTOR XIII; FIBRINOLYSIS; CLOT MECHANICS; ALTERNATIVE MRNA FIBRINOGEN SPLICING; FIBRIN CLOT STRUCTURE AND CORONARY ARTERY DISEASE; FIBRIN CLOT STRUCTURE AND VENOUS THROMBOSIS
POLYMORPH-PLATELET INTERACTIONSNETRIN-1; Netrin-1 in Atherosclerosis; The Relationship Between Netrin-1 and Inflammation; Antiplatelet Therapy and Netrin-1; ANTIPLATELET THERAPY AS A POSSIBLE NOVEL APPROACH TO INHIBITING ATHEROSCLEROSIS; CONCLUSIONS; REFERENCES; 5 -- Mathematical Models of Thrombus Formation and Fibrinolysis; INTRODUCTION; OVERVIEW OF DIFFERENTIAL EQUATIONS; BRIEF BIOLOGICAL BACKGROUND; Coagulation and Platelet Aggregation; Fibrin Polymerization; Fibrinolysis; MODELS OF THROMBIN GENERATION AND THROMBUS FORMATION; Zero-Dimensional Models
ROLE OF SMOKING, DIABETES, AND GLYCATIONSTROKE, PERIPHERAL DISEASE, AND ANEURYSM; MEDICATION AND CLOT STRUCTURE; CONCLUSIONS; REFERENCES; 4 -- The Role of Platelets in the Pathophysiology of Atherosclerosis and Its Complications; PLATELETS; PLATELET ACTIVATION AND FUNCTION; Thrombin; Adenosine Diphosphate; Thromboxane A2; PLATELETS AS MODULATORS OF INFLAMMATION: RELEVANCE TO ATHEROSCLEROSIS; THE ROLE OF INFLAMMATION IN ATHEROSCLEROSIS; MONOCYTES; The Role of Monocytes in Atherosclerosis; Monocyte Phenotypes and Their Differential Contribution to Atherosclerosis; Monocyte-Platelet Interactions
Summary Cardiovascular Thrombus: From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions provides a comprehensive, up-to-date presentation of the research and clinical practices as related to the contemporary aspects of the diagnosis and management of cardiovascular thrombosis. The formation, identification and management of cardiovascular thrombus is of paramount importance for researchers and practicing physicians, yet it remains one of the most challenging diagnostic and clinical scenarios. This important reference connects between research, up-to-date clinical knowledge, and the technological tools available for diagnosis and management of thrombus in cardiovascular medicine. The book includes comprehensive descriptions and review of pathology, clinical presentations, diagnosis, pharmacotherapy, interventions and future trends. It is the perfect reference for basic science students and researchers in general and interventional cardiology, general and interventional radiology, vascular medicine specialists, and vascular, general and cardiac surgeons. Provides comprehensive presentation of the pathophysiology, clinical presentations and diagnosis of cardiovascular thrombosisIncludes the most up-to-date information on the practical management of patients with thrombus related conditionsWritten by the leading experts in the fieldDescribes the current and upcoming pharmacotherapy and technology available for thrombus research and treatment
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF file page (EBSCO, viewed August 24, 2018)
Subject Cardiovascular system -- Popular works
Cardiovascular system -- Treatment -- Popular works
Cardiovascular System
Thrombosis
Cardiovascular system.
HEALTH & FITNESS / Diseases / General.
MEDICAL / Clinical Medicine.
MEDICAL / Diseases.
MEDICAL / Evidence-Based Medicine.
MEDICAL / Internal Medicine.
Genre/Form Popular works.
Form Electronic book
ISBN 0128126167 (electronic bk.)
9780128126165 (electronic bk.)