| Description |
1 online resource |
| Series |
Advances in biochemistry in health and disease ; v. 5 |
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Advances in biochemistry in health and disease ; v. 5.
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| Contents |
880-01 Molecular Mechanisms of Remodeling in Pressure and Volume Overload Hypertrophy and Heart Failure -- beta-Adrenergic Receptor Signaling in Heart Failure / Grace Jung Ah Lee, Lin Yan, Dorothy E. Vatner, Stephen F. Vatner -- Remodeling of Potassium Channels in Cardiac Hypertrophy / Tetsuo Sasano, Junko Kurokawa -- Role of Gender in Ca² Cycling and Cardiac Remodeling Due to Heart Failure / Naranjan S. Dhalla, Amrit Malik, Shelly Zieroth, Paramjit S. Tappia -- The Failing Heart: Is It an Inefficient Engine or an Engine Out of Fuel? / Waleed G.T. Masoud, Alexander S. Clanachan, Gary D. Lopaschuk -- Regulation of Cardiac Hypertrophic Remodeling by the USP15/SLIM1 Pathway / Hiroto Nakajima -- Role of Galectin-3 Pathways in the Pathogenesis of Cardiac Remodeling and Heart Failure / Lili Yu, Rudolf A. de Boer -- A Mitochondriocentric Pathway to Cardiomyocyte Necrosis: An Upstream Molecular Mechanism in Myocardial Fibrosis / Adedayo A. Adeboye, Kevin P. Newman, Dwight A. Dishmon, Shadwan Alsafwah |
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880-01/(S Part I: Molecular mechanisms of remodeling in pressure and volume overload hypertrophy and ehart failure -- β-adrenergic receptor signaling pathway in heart failure -- Remodeling of potassium channels in cardiac hypertrophy -- Role of gender in Ca2+ cycling and cardiac remodeling due to heart failure -- The failing heart: is it an inefficient engine or an engine out of fuel-- Regulation of cardiac hypertrophic remodeling by the USP15/SLIM1 pathway -- Role of galectin-3 pathways in the pathogenesis of cardiac remodeling and heart failure -- A mitochondriocentric pathway to cardiomyocyte necrosis: an upstream molecular mechanism in myocardial fibrosis -- The ACE2/Ang (1-7) pathway in cardiac remodeling due to pressure-overload -- Local actions of natriuretic peptides and nitric oxide in cardiac remodelling: Implications for therapy -- Modulating G protein-coupled receptors to effect reverse cardiac remodeling |
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Part I. Molecular mechanisms of remodeling in pressure and volume overload hypertrophy and heart failure -- part II. Molecular mechanisms of remodeling after myocardial injury and infarction |
| Summary |
The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| In |
Springer eBooks |
| Subject |
Ventricular remodeling.
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Diseases.
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Cardiovascular system -- Physiology
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Ventricular Function
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Pathological Conditions, Anatomical
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Cardiovascular Physiological Phenomena
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Pathological Conditions, Signs and Symptoms
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Disease
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Circulatory and Respiratory Physiological Phenomena
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Phenomena and Processes
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Ventricular Remodeling
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HEALTH & FITNESS -- Diseases -- Heart.
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MEDICAL -- Cardiology.
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Diseases
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Ventricular remodeling
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| Form |
Electronic book
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| Author |
Jugdutt, Bodh I.
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Dhalla, Naranjan S.
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| ISBN |
9781461459309 |
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1461459303 |
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1489993835 |
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9781489993830 |
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1299335624 |
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9781299335622 |
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