| Description |
1 online resource (xiv, 404 pages) : illustrations (some color) |
| Series |
Methods in molecular biology, 1940-6029 ; volume 1816 |
|
Methods in molecular biology (Clifton, N.J.) ; v. 1816. 1064-3745
|
| Contents |
Part I: Overview 1. Experimental Models of Cardiovascular Diseases -- Overview -- Jae Gyun Oh and Kiyotake Ishikawa Part II :In Silico Models 2. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity Joshua Mayourian, Eric A. Sobie, and Kevin D. Costa Part III: In Vitro Models 3. Isolation of Atrial and Ventricular Cardiomyocytes for In Vitro Studies Jelena Plačkić and Jens Kockskämper 4. Cardiomyocyte Differentiation from mouse Embryonic Stem Cells Adam T Lynch, Silvia Mazzotta, and Stefan Hoppler 5. Cardiomyocyte Differentiation from Human Embryonic Stem Cells Silvia Mazzotta, Adam T Lynch, and Stefan Hoppler 6. Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes using Embryoid Bodies Takeshi Hatani1, Kenji Miki, and Yoshinori Yoshida 7. Measuring Cardiomyocyte Contractility and Calcium Handling In Vitro Przemek A. Gorski, Changwon Kho, and Jae Gyun Oh Part IV: Ex Vivo Models 8 |
| Summary |
This book provides methodological information on establishing reliable and reproducible experimental models of cardiovascular diseases. Chapters detail practical protocols from expert laboratories focusing on cardiovascular research, leading to novel discoveries in cardiac biology, and the development of effective therapeutic approaches. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Experimental Models of Cardiovascular Disease: Methods and Protocols aims to ensure successful results in the further study of this vital field |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerProtocol viewed July 11, 2018) |
| Subject |
Cardiovascular system -- Diseases -- Mathematical models
|
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Cardiovascular system -- Diseases.
|
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Mathematical models.
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Cardiovascular Diseases
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Models, Theoretical
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Models, Animal
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mathematical models.
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Medical research.
|
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Science -- Life Sciences -- Biology -- Molecular Biology.
|
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Cardiovascular system -- Diseases
|
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Mathematical models
|
| Genre/Form |
Laboratory manuals
|
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Laboratory manuals.
|
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Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Ishikawa, Kiyotake, editor.
|
| ISBN |
9781493985975 |
|
1493985973 |
|
1493985965 |
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9781493985968 |
|
