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E-book

Title Role of capsaicin in oxidative stress and cancer / Sanjay K. Srivastava, editor
Published Dordrecht : Springer, ©2013

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Description 1 online resource (ix, 178 pages) : illustrations (some color)
Series Diet and cancer ; 3
Diet and cancer (Series) ; 3
Contents Role of Capsaicin in Cancer Prevention -- Role of Death Receptors Belonging to the TNF Family in Capsaicin-Induced Apoptosis of Tumor Cells -- Role of Capsaicin in Prostate Cancer -- Capsaicin and the Urinary Bladder -- Inhibition of Pancreatitis and Carcinogenesis by Capsaicin -- Cytochrome P450-Dependent Modification of Capsaicinoids: Pharmacological Inactivation and Bioactivation Mechanisms -- The Cancer-Suppressing and -Promoting Actions of Capsaicin -- Oxidative Stress by Capsaicin in Cancer
Summary This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival p
Analysis Medicine
Oncology
Gene expression
Cytology
Biomedicine
Cancer Research
Apoptosis
Pharmacology/Toxicology
Bibliography Includes bibliographical references and index
Subject Cancer -- Nutritional aspects.
Capsaicin -- Physiological effect
Nutrition.
Capsaicin -- physiology
Neoplasms
Nutritional Physiological Phenomena
HEALTH & FITNESS -- Diseases -- Cancer.
MEDICAL -- Oncology.
Médecine.
Cancer -- Nutritional aspects.
Capsaicin -- Physiological effect.
Genre/Form Electronic books
Form Electronic book
Author Srivastava, Sanjay K
ISBN 9789400763173
9400763174
9400763166
9789400763166