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Title Phytopharmaceuticals in cancer chemoprevention / edited by Debasis Bagchi, Harry G. Preuss
Published Boca Raton, Fla. : CRC Press, ©2005

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Description 1 online resource (665 pages, [4] color plates) : illustrations
Series CRC series in modern nutrition science
CRC series in modern nutrition science.
Contents Front cover; Series Preface; Preface; Editors; Contributors; Table of Contents; Section I; CH 1 Epidemiology of Cancer: an Overview; CONTENTS; 1.1 EPIDEMIOLOGY; 1.2 CANCER: BASIC FACTS; 1.2.1; 1.2.2; 1.3 CANCER TERMS; 1.3.1; 1.3.2; 1.3.3; 1.3.4; 1.4 CANCER: STATISTICS; 1.4.1; 1.4.2; 1.4.3; 1.4.4; 1.4.5; 1.5 CONCLUSION; REFERENCES; Section II; CH 2 Role of DNA Methylation in Cancer and Chemotherapy; CONTENTS; 2.1 INTRODUCTION; 2.2 MAINTENANCE OF METHYLATION PATTERNS IN GENOMIC DNA; 2.3 ROLE OF DNA HYPERMETHYLATION IN TUMORIGENESIS; 2.4 DNA HYPOMETHYLATION IN TUMOR DEVELOPMENT
2.5 DNA METHYLATION AND CHEMOTHERAPEUTIC RESPONSE2.6 CONCLUSIONS; ACKNOWLEDGMENT; REFERENCES; CH 3 Metals, Metalloids, and Cancer; CONTENTS; 3.1 INTRODUCTION: METALS AND METALLOIDS; 3.2 EPIDEMIOLOGY: THE CASE FOR METALS AND CANCER; 3.3 CARCINOGENIC METALS; 3.3.1; 3.3.2; 3.3.3; 3.3.4; 3.3.5; 3.3.6; 3.3.7; 3.3.8; 3.4 MECHANISMS OF CANCER CAUSATION BY METALS; 3.4.1; 3.4.2; 3.4.3; 3.4.4; 3.5 CONCLUSIONS; REFERENCES; CH 4 Molecular Mechanisms of Asbestos- and Silica-Induced Lung Cancer; CONTENTS; 4.1 INTRODUCTION; 4.2 BASIC MOLECULAR EVENTS IN CARCINOGENESIS; 4.2.1; 4.2.2
4.3 LINKAGE BETWEEN SILICA AND LUNG CANCER4.3.1; 4.3.2; 4.3.3; 4.3.4; 4.4 ASBESTOS, A POTENT AND ESTABLISHED CARCINOGEN; 4.4.1; 4.4.2; 4.4.3; 4.5 CONCLUSIONS; REFERENCES; CH 5 Involvement of Receptor Tyrosine Kinases in Lung Cancer: Clinical Importance; CONTENTS; 5.1 INTRODUCTION; 5.2 RECEPTOR TYROSINE KINASES (RTKS); 5.2.2; 5.2.3; 5.3 ROLE OF cMET cKIT AND EGFR; 5.4 ROLE OF REACTIVE OXYGEN SPECIES; 5.5 RECEPTOR TYROSINE KINASES AS TARGET FOR ANTI-CANCER THERAPY; 5.6 CONCLUSION; REFERENCES; CH 6 Free Radicals, Environmental Radiation, and Cancer; CONTENTS; 6.1 FREE-RADICAL CHEMISTRY; 6.1.1
6.1.26.2 RADIATION BIOLOGY AND CANCER; 6.3 RADIATION AND THE ENVIRONMENT; REFERENCES; CH 7 Smokeless Tobacco, Oxidative Stress, and Oral Cancer; CONTENTS; 7.1 INTRODUCTION; 7.2 PREPARATION OF SMOKELESS TOBACCO EXTRACT (STE); 7.3 SMOKELESS TOBACCO EXTRACT, FREE-RADICAL FORMATION, AND LIPID PEROXIDATION; 7.4 SMOKELESS-TOBACCO-INDUCED EXCRETION OF URINARY METABOLITES; 7.5 SMOKELESS TOBACCO EXTRACT, CYTOTOXICITY, AND LDH LEAKAGE IN J774A.1 MACROPHAGE AND PERITONEAL MACROPHAGE CELLS; 7.6 SMOKELESS TOBACCO EXTRACT AND FREE-RADICAL SCAVENGING EFFECTS OF COMMON ANTIOXIDANTS IN MACROPHAGE CELLS
7.7 subchronic effects of smokeless tobacco extract on hepatic lipid peroxidation and the increased excretion of urinary metabolites7.8 chronic effects of smokeless tobacco on the histopathology of rat livers and induction of hsp90; 7.9 cell viability and trypan blue exclusion technique of normal human oral keratinocytes (nhok) treated with ste; 7.10 smokeless tobacco and superoxide anion production in human oral keratinocytes; 7.11 smokeless tobacco and lipid peroxidation of human oral keratinocytes
Summary During the past decade, a significant amount of research has been conducted on phytopharmaceuticals. Today, a growing body of evidence demonstrates the efficacy of a wide variety of natural products and affirms their potential in the treatment of cancer. Phytopharmaceuticals in Cancer Chemoprevention focuses on the role of natural supplements in cancer prevention and therapy. The first section covers cancer epidemiology, as well as cancer statistics, current therapies, and potential toxicities involved with existing cancer drugs. The second section begins by discussing the pathophysiology of c
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cancer -- Chemoprevention.
Carcinogenesis.
Cancer -- Pathophysiology.
Materia medica, Vegetable.
Dietary supplements.
Medicine, Botanic.
Neoplasms -- prevention & control
Phytotherapy
Plant Extracts -- therapeutic use
Dietary Supplements
Drug Discovery
Carcinogenesis
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Medicine, Botanic
Cancer -- Chemoprevention
Cancer -- Pathophysiology
Carcinogenesis
Dietary supplements
Materia medica, Vegetable
Phytothérapie.
Neoplasias (quimioterapia;fisiopatologia)
Carcinoma.
Plantas medicinais (quimioterapia)
Cancer -- Chimioprévention.
Form Electronic book
Author Bagchi, Debasis, 1954-
Preuss, Harry G
ISBN 0203506707
9780203506707
0849315603
9780849315602