| Description |
1 online resource (xxiv, 239 pages) : illustrations |
| Series |
Advances in experimental medicine and biology ; v. 575 |
|
Advances in experimental medicine and biology ; v. 575.
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| Contents |
Topic I. Structure and function. Peptide substrates of dipeptidyl peptidases / Inger Brandt [and others]. Phosphorus-containing inhibitors of proteolytic enzymes / Angel Stöckel-Maschek [and others]. Biochemical properties of recombinant prolyl dipeptidases DPP-IV and DPP8 / Xin Chen. Prediction of dipeptidyl peptidase (DP) 8 structure by homology modelling / Melissa R. Pitman, R. Ian Menz, and Catherine A. Abbott -- Topic II. DPIV-related enzymes. Structure and function in dipeptidyl peptidase IV and related proteins / Mark D. Gorrell [and others]. Expression and function of dipeptidyl peptidase IV and related enzymes in cancer / Petr Busek [and others]. DP8 and DP9 have extra-enzymatic roles in cell adhesion, migration, and apoptosis / Denise M.T. Yu [and others]. In vivo effects of a potent, selective DPPII inhibitor: UAMC00039 is a possible tool for the elucidation of the physiological function of DPPII / Marie-Berthe Maes [and others]. Expression of dipeptidyl peptidase IV-like enzymes in human peripheral blood mononuclear cells / Sabine Wrenger [and others]. Dipeptidyl peptidase 8 has post-proline dipeptidyl aminopeptidase and prolyl endopeptidase activities / Joohong Park [and others]. Prolyl endopeptidase cleaves the apoptosis rescue peptide humanin and exhibits and unknown post-cysteine cleavage specificity / Joachim Wolfgang Bär [and others]. Distribution of dipeptidyl peptidase IV-like activity enzymes in canine and porcine tissue sections by RT-PCR / Leona Wagner [and others] -- Topic III. Metabolic disorders. Relative contribution of incretins to the glucose lowering effect of DP IV inhibitors in type 2 diabetes mellitus (T2DM) / Simon A. Hinke, Raymond A. Pederson, and Christopher H.S. McIntosh. Dipeptidyl peptidase IV: a molecular switch of vascular actions of neuropeptide Y / Lijun Li, Hans-Ulrich Demuth, and Zofia Zukowska -- Topic IV. Immune disorders. Dipeptidylpeptidase IV (DPIV) and alanyl-aminopeptidases (AAPs) as a new target complex for treatment of autoimmune and inflammatory diseases: proof of concept in a mouse model of colitis / Ute Bank [and others]. Dipeptidyl peptidases and inflammatory bowel disease / Catherine A. Abbott [and others]. Possible role of DP IV inhibitors in acne therapy / Anja Thielitz [and others]. Dipeptidyl peptidase-IV activity and/or structure homologs (DASH): contributing factors in the pathogenesis of rheumatic diseases? / Eva Balaziova [and others] -- Topic V. Neuronal diseases. Dipeptidyl peptidase IV (DP IV, CD26) and aminopeptidase N (APN, CD13) as regulators of T cell function and targets of immunotherapy in CNS inflammation / Aliza Biton [and others]. CD26/DP IV in T cell activation and autoimmunity / Vera Preller [and others]. DPIV/CD26 and FAP in cancer: a tale of contradictions / Melanie L. Sulda, Catherine A. Abbott, and Martin Hildebrandt. Type-II transmembrane prolyl dipeptidases and matrix metalloproteinases in membrane vesicles of active endothelial cells / Monica Salamone [and others]. Extra-enzymatic roles of DPIV and FAP in cell adhesion and migration on collagen and fibronectin / Xin M. Wang [and others]. Role of neuropeptide Y and dipeptidyl peptidase IV in regulation of Ewing's sarcoma growth / Joanna Kitlinska [and others]. The role of CD26/DPP IV in preservation of early pulmonary graft function / Florian Johannes Jung [and others] |
| Summary |
Dipeptidyl Aminopeptidases exert a modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. This book focuses on various topics, including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and more |
| Analysis |
suikerziekte |
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diabetes |
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immunologie |
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immunology |
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infectieziekten |
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infectious diseases |
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biochemie |
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biochemistry |
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stofwisselingsstoornissen |
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metabolic disorders |
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biomedische wetenschappen |
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biomedicine |
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neurowetenschap |
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neuroscience |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
CD antigens -- Congresses
|
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Aminopeptidases -- Congresses
|
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CD26 antigen.
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Aminopeptidases.
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Dipeptidyl-Peptidases and Tripeptidyl-Peptidases -- physiology
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Dipeptidyl-Peptidases and Tripeptidyl-Peptidases -- therapeutic use
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Dipeptidyl Peptidase 4
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Aminopeptidases
|
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MEDICAL -- Immunology.
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Dipeptidyl Peptidases -- physiology.
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Dipeptidyl Peptidases -- therapeutic use.
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Aminopeptidases.
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Antigens, CD26.
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CD antigens.
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Biomédecine.
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Sciences de la vie.
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CD26 antigen
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Aminopeptidases
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CD antigens
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| Genre/Form |
proceedings (reports)
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Conference papers and proceedings
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Conference papers and proceedings.
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Actes de congrès.
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| Form |
Electronic book
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| Author |
Lendeckel, Uwe
|
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Reinhold, Dirk.
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Bank, Ute.
|
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International Conference on Dipeptidyl Aminopeptidases (2nd : 2005 : Magdeburg, Germany)
|
| ISBN |
9780387328249 |
|
0387328246 |
|
0387290583 |
|
9780387290584 |
|
1280726636 |
|
9781280726637 |
|
9786610726639 |
|
6610726639 |
|
