"A practical example of the increasingly important role of perfusion in clinical practice is the identification of infarct core and ischemic penumbra in acute stroke patients. In early 2015, several clinical trials that focused on endovascular treatment of large vessel occlusion in stroke patients demonstrated remarkable outcomes. The most successful trials used perfusion metrics for patient selection, specifically to identify patients with a small core, sufficient salvageable tissue, and ample collateral flow"--Provided by publisher