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Book Cover
E-book
Author Langham, M. E. (Maurice E.)

Title Ischemia and loss of vascular autoregulation in ocular and cerebral diseases : a new perspective / Maurice E. Langham
Published New York : Springer, ©2009

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Description 1 online resource (xix, 192 pages) : illustrations
Series Lecture notes in mathematics ; 762
Lecture notes in mathematics ; 762. 1617-9692
Contents Ch. 1 "In vivo" manometric studies of the steady state intraocular pressure and the intraocular pressure pulse in animals and man -- Ch. 2 Rate of formation of the aqueous humor -- Ch. 3 Steady state intraocular pressure/flow relations in dead and living animal and human eyes -- Ch. 4 Homeostasis, autoregulation, and relative ischemia -- Ch. 5 Pressure/volume relation in eyes of dead and living animal and human eyes -- Ch. 6 Ocular perfusion pressure and its influence on the intraocular pressure pulse -- Ch. 7 Direct and indirect measurements of ocular blood flow in anesthetized and conscious animals and humans -- Ch. 8 Morphology and hydrodynamics of the chamber angle draining the aqueous humor -- Ch. 9 Sympathetic nerve innervation of the eye and the actions of the adrenergic neuron transmitter norepinephrine on intraocular pressure and ocular blood flow -- Ch. 10 Manometric studies on the intraocular pressure and vascular circulation in ophthalmic disease -- Ch. 11 Noninvasive studies on the IOP, PA and blood flow autoregulation in healthy and diseased eyes -- Ch. 12 Effect of posture and corneal thickness on the measurement of the intraocular pressure -- Ch. 13 The Langham pneumatic analogue and digitized tonometers -- Ch. 14 Calibration of the intraocular pressure and the intraocular pressure pulse using the Langham pneumatic tonometer -- Ch. 15 Theory of the Langham tonometer
Ch. 16 Intraocular pressure/pulse amplitude relation in healthy animal and human eyes -- Ch. 17 Intraocular pressure/pulse amplitude relation and loss of autoregulation in ocular diseases -- Ch. 18 Autoregulation of the intraocular pressure and the ocular blood flow -- Ch. 19 Evaluation of ocular ischemia and the loss of autoregulation for the early detection of ocular vascular diseases -- Ch. 20 Action of drugs on ocular blood flow and on the intraocular pressure/pulse amplitude relation -- Ch. 21 Confluence and integration of therapies based on modulation of the intraocular pressure and ocular blood flow -- Ch. 22 Longitudinal therapeutic studies -- Ch. 23 Ophthalmodynamometry, the opthalmic arterial pressure and the effect of increased vascular resistance proximal and distal to the ophthalmic artery on ocular blood flow, the IOP/PA relation and vision -- Ch. 24 Ophthalmodynamometry -- Ch. 25 Autoregulation of the intraocular pressure and blood flow in the human eye -- Ch. 26 Objective measure of the diastolic and systolic ophthalmic arterial pressures -- Ch. 27 Ophthalmic arterial pressure in healthy subjects -- Ch. 28 Relation between the ophthalmic arterial pressure and the intraocular pressure/pulse amplitude relation -- Ch. 29 Modulation of the intraocular pressure/pulse amplitude relation in subjects with stenosis of the internal carotid artery -- 30 Alzheimer's disease and the eye -- Ch. 31 Ocular perfusion pressure and the visual threshold
Summary From the introduction of this book: 'The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 years on the physiology of intraocular pressure, ocular blood flow and the relation of these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the author's own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby led to new methods of diagnosis and therapy'
Bibliography Includes bibliographical references (pages 187-188) and index
Notes Print version record
Subject Ischemia.
Eye -- Blood-vessels -- Diseases.
Peripheral vascular diseases -- Diagnosis.
Cerebral ischemia.
Eye -- blood supply
Ischemia -- complications
Homeostasis -- physiology
Intraocular Pressure -- physiology
Peripheral Vascular Diseases -- diagnosis
Regional Blood Flow -- physiology
Ischemia
Brain Ischemia
Ischemia -- complications.
Homeostasis -- physiology.
Intraocular Pressure -- physiology.
Peripheral Vascular Diseases -- diagnosis.
Regional Blood Flow -- physiology.
Ischemia.
Eye -- Blood-vessels -- Diseases.
Cerebral ischemia.
Eye -- blood supply.
Cerebral ischemia
Eye -- Blood-vessels -- Diseases
Ischemia
Peripheral vascular diseases -- Diagnosis
Form Electronic book
ISBN 9780387097169
0387097163