Description |
1 online resource (512 pages) : illustrations |
Contents |
The normal bone marrow -- Special techniques applicable to bone marrow diagnosis -- Infection and reactive changes -- Acute myeloid leukaemia, the myelodysplastic syndromes and histiocytic neoplasms -- Chronic myeloproliferative and myeloproliferative/myelodysplastic disorders -- Lymphoproliferative disorders -- Multiple myeloma and related disorders -- Disorders of erythropoiesis, granulopoiesis and thrombopoiesis -- Miscellaneous disorders -- Metastatic tumours -- Diseases of bone |
Summary |
In this book we have set out to provide a practical guide to bone marrow diagnosis, based on an integrated assessment of peripheral blood and bone marrow aspirate films, trephine biopsy sections and various supplementary investigations. We believe that a trephine biopsy specimen should not be examined and interpreted in isolation. We have therefore discussed the clinical context of bone marrow diagnosis and have given equal weight to cytological and histological features. Since bone marrow diagnosis is no longer based on morphological features alone, this edition discusses in considerable detail the role of immunophenotypic, cytogenetic and molecular genetic analysis. We have dealt very fully with haematological disorders for which bone marrow examination is commonly performed. However, we have also sought to be as comprehensive as possible, including whatever information is available on uncommon and rare disorders so that the book will serve as a useful reference source. When possible, we have illustrated rare as well as common conditions and have cited the relevant scientific literature extensively. In this edition we have introduced a new section entitled 'Problems and pitfalls' which we believe will be of value. We have also expanded the description of technical methods. We hope that haematologists and histopathologists will continue to find this book a useful aid in their day-to-day practice and that trainees in these disciplines will find it indispensable |
Bibliography |
Includes list of abbreviations, bibliographical references at chapter ends, appendix, and index |
Notes |
Print version record |
Subject |
Bone marrow -- Histopathology
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Bone marrow -- Diseases.
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Bone Marrow Diseases
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Bone marrow -- Diseases
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Form |
Electronic book
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Author |
Clark, David M., MD.
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Lampert, Irvin A.
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Wilkins, Bridget, 1959-
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ISBN |
9780470756898 |
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0470756896 |
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