| Description |
1 online resource (xvii, 265 pages) : illustrations |
| Series |
Falk symposium ; 155 |
|
Falk symposium (Series) ; 155.
|
| Contents |
Metabolism of bile acids -- Analysis of mice deficient in the bile acid biosynthetic enzyme 3?-hydroxy-?5-C27-steroid oxidoreductase (HSD3B7) -- Role of oxysterols and cholestenoic acids in a crosstalk between the brain and the liver -- Activation of a G-protein coupled receptor by conjugated bile acids in primary hepatocytes and liver: effects on glucose metabolism -- Discovery of a novel oxysterol, 5-cholesten-3?, 25-diol 3-sulphate, in nuclei and mitochondria following over-expression of the gene encoding StarD1 -- Hepatobiliary transport of bile acids -- Role of Ntcp phosphorylation in cAMP-mediated stimulation of hepatic bile acid uptake -- The concept of basolateral efflux pumps of the hepatocyte -- Insights into the regulation of expression of human OST?-OST? -- Regulation of hepatobiliary transport proteins in chronic cholestasis -- Assessment of inhibitory effect of many therapeutically important drugs on bile acid transport by NTCP, BSEP and other transporters -- Extrahepatocytic transport and actions of bile acids -- Extrahepatocytic transport of bile acids: the role of the cholangiocyte -- Molecular mechanisms of intestinal basolateral bile acid transport -- Regulation of intestinal bile acid transport in health and disease -- Evidence for a role of the FXR-driven intestinal regulatory factor FGF-19 upon cholestyramine and chenodeoxycholic acid treatment and during the diurnal regulation of bile acid synthesis in humans -- Nuclear receptor regulation -- Bile acid-like hormones function as ligands for the nematode orphan nuclear receptor DAF-12 and govern dauer formation, reproduction and lifespan -- Regulation of CYP7A1 by nuclear receptor signalling in human liver cells -- Regulation of hepatic and intestinal bile acid transport by FXR-controlled pathways -- Regulation ofbile acid homeostasis by the nuclear bile acid receptor FXR and fibroblast growth factor 15 -- Bile salts activate endothelial no synthase in sinusoidal endothelial cells of the liver via the G-protein coupled receptor TGR5 -- Bile acids, cellular injury, and disease mechanisms -- Bile salt-induced CD95 activation -- Role of Fas and caspase 8 in glycochenodeoxycholic acid-induced hepatocellular apoptosis in human liver cell lines -- Disulphated progesterone metabolites in urine relate to pruritus in intrahepatic cholestasis of pregnancy treated with ursodeoxycholic acid -- Adolf windaus prize lecture: primary biliary cirrhosis: from ursodeoxycholic acid towards targeting strategies for therapies -- Bile acids, cellular injury, and hepatic fibrosis -- Bile acids and liver fibrosis Causative agent and therapeutic tool -- Mechanisms of bile acid-induced cell death in vivo and in vitro -- Bile acids enhance cellular motility of the hepatic myofibroblast-like cell through the regulation of p38/JNK signalling -- Bile acids as therapeutic agents: mechanisms and actions -- Side-chain-shortened bile acids for the treatment of cholestasis: lessons from nor-ursodeoxycholic acid -- Ursodeoxycholic acid-disulphate (SUDCA) a potent chemopreventive agent against colon cancer -- Prevention of cholesterol gallstones by the potent cholesterol absorption inhibitor ezetimibe in gallstone-susceptible C57L/J mice -- Tauroursodeoxycholic acid antagonizes taurolithocholic acid-induced cholestasis via a cooperative protein kinase C-and protein kinase A-dependent signalling pathway in the perfused rat liver -- Bile acids in the treatment of cholestatic liver disease -- Ursodeoxycholic acid for the treatment of primary sclerosing cholangitis -- Role of polymorphisms in genes involved in bile aciddetoxification pathways in primary sclerosing cholangitis -- High-dose ursodeoxycholic acid in the treatment of primary sclerosing cholangitis -- Primary sclerosing cholangitis: bile duct and colonie carcinomas after long-term ursodeoxycholic acid |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Bile acids -- Congresses
|
|
Bile Acids and Salts
|
|
Bile acids.
|
|
Gallensäuren
|
| Genre/Form |
Conference papers and proceedings.
|
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Conference papers and proceedings.
|
|
Actes de congrès.
|
| Form |
Electronic book
|
| Author |
Keppler, D. (Dietrich)
|
| ISBN |
9781402062520 |
|
1402062524 |
|
