| Description |
1 online resource (xx, 366 pages) : illustrations |
| Contents |
Regulation of porin gene expression by the two-component regulatory system EnvZ/OmpR / Don Walthers, Alvin Go and Linda J. Kenney -- The Structures of general porins / Georg E. Schulz -- Role of bacterial porins in antibiotic susceptibility of gram-negative bacteria / Jean-Marie Pagés -- Porins of the outer membrane of Pseudomonas aeruginosa / Robert E.W. Hancock and Sandeep Tamber -- Regulation of bacterial porin function / Arnaud Baslé and Anne H. Delcour -- Reconstitution of general diffusion pores from bacterial outer membranes / Christophe Danelon and Mathias Winterhalter -- OmpA/OprF: slow porins or channels produced by alternative folding of outer membrane proteins / Etsuko Sugawara and Hiroshi Nikaido -- Drug efflux and protein export through channel-tunnels / Christian Andersen -- Structure-function relationships in sugar-specific porins / Tilman Schirmer -- Functional reconstitution of specific porins / Roland Benz and Frank Orlik -- Energy-coupled outer membrane iron transporters / Volkmar Braun and Michael Braun -- Structural and functional aspects of the vitamin B12 receptor BtuB / Robert J. Kadner, David P. Chimento and Nathalie Cadieux -- Structure and function of mitochondrial (eukaryotic) porins / Roland Benz -- Mitochondrial porins in mammals : insights into functional roles from mutant mice and cells / Keltoum Anflous and William J. Craigen -- Gene family expression and multitopological localization of eukaryotic porin/voltage dependent anion-selective channel (VDAC) : intracellular trafficking and alternative splicing / Vito De Pinto and Angela Messina -- Function of the outer mitochondrial membrane pore (voltage-dependent anion channel) in intracellular signaling / Mikhail Vyssokikh and Dieter Brdiczka |
| Summary |
This first book dedicated to the topic relates the known physiological functions of porins to their molecular structure and mechanism, as documented by various in vitro and in vivo methods, including the generation of null mutants in mice. For the first time, it brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function. With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist w |
| Analysis |
Molecular Biology and Genetics |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Molecules.
|
|
Proteins -- Structure.
|
|
Bacterial Outer Membrane Proteins.
|
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Eukaryotic Cells.
|
|
Porins.
|
| Form |
Electronic book
|
| Author |
Benz, Roland, 1943-
|
|
John Wiley & Sons.
|
| ISBN |
1280519622 |
|
3527307753 (print. edition) |
|
3527603875 (electronic bk.) |
|
3527604227 (electronic bk.) |
|
9781280519628 |
|
9783527307753 (print. edition) |
|
9783527603879 (electronic bk.) |
|
9783527604227 (electronic bk.) |
|
