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Title Routledge handbook of sport and exercise systems genetics / edited by J. Timothy Lightfoot, Monica J. Hubal, and Stephen M. Roth
Published Abingdon, Oxon ; New York, NY : Routledge, 2019

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Description 1 online resource (xxviii, 514 pages : illustrations, tables
Series Routledge international handbooks
Routledge international handbooks.
Contents Cover; Half Title; Title Page; Copyright Page; Table of contents; List of Figures; List of Tables; List of Contributors; Foreword; Preface; Introduction; References; Section 1 General systems genetics; 1 Why study the systems genetics of sport and exercise?; Introduction; Exercise systems genomics; Exercise presents a high stress; however, the body is able to survive by maintaining its homeostasis ... ; Exercise systems genetics versus inactivity systems genetics; Physical inactivity is a necessary reference group to show healthy exercise effects -- and turns ..
A biased positive look to the futureA projection into where technology seems to be taking physical inactivity; Multiple, biased, concerned looks to the future; New technology is often based upon reducing physical activity; Inheritance of low voluntary running behavior; Does epigenetics play a role in type 2 diabetes and in physical inactivity?; Low voluntary running animal model to mimic increased human inactivity; The high economic costs of physical inactivity are contributing in their small way to the bankruptcy of our children's future cost of living
What systems genetics could do for humansReferences; 2 Expansion of knowledge and advances in genetics for quantitative analyses; Introduction; The Human Genome Project; Advances in sequencing; Association studies; Noncoding sequences; Noncoding RNA and antisense sequences; MicroRNAs; Exosomes; Epigenetics; Summary; References; 3 human systems genetic modeling used in exercise; Introduction; Study of families; What are families?; Quantifying family data; Twin studies; Biology of twins and twinning; The classical twin model; Basic concepts of the twin model; The univariate twin model
Multivariate twin modelsMZ discordant pairs to study causal associations; Adoption studies; Twin family designs; Genome-wide association studies; The future in the era of molecular genetics; Further reading; References; 4 The translation of systems genetics of exercise to everyday life; Introduction; Theoretical foundations of exercise interventions; Translating exercise genomics into practice; Using genetic information to enhance exercise adherence; Using genetic information to enhance exercise prescription and intervention
Using genetic information to identify individuals at risk for exercise dropoutConclusion; References; Section 2 Systems genetics of physical activity; 5 Is physical activity regulated by genetics? Evidence from animal models; What is physical activity in an animal model?; Heritability; Genetic architecture; Genetic mapping; Fine-mapping approaches; Future directions; References; 6 Is physical activity regulated by genetics? Evidence from studies in humans; Introduction; Twin studies; Physical activity phenotypes; Meta-analyses; Results for total physical activity
Summary "The Routledge Handbook of Sport and Exercise Systems Genetics constitutes the most authoritative and comprehensive reference in this critical area of study, consolidating knowledge and providing a framework for interpreting future research findings. Taking an approach which covers single gene variations, through genomics, epigenetics and proteomics, to environmental and dietary influences on genetic mechanisms, the book is divided into six sections. It examines state-of-the-art genetic methods, applies its approach to physical activity, exercise endurance, muscle strength and sports performance, and discusses the ethical considerations associated with genetic research in sport and exercise"-- Provided by publisher
Bibliography Includes bibliographical references and index
Notes J. Timothy Lightfoot is the Omar Smith Endowed Chair in Kinesiology andthe Director of the Sydney and JL Huffines Institute for Sports Medicine and Human Performance at Texas A & M University in College Station, Texas (USA), and holds the rank of Professor of joint appointments on the Texas A & M Genetics Faculty and the Texas A & M Institute for Genome Sciences and Society. His research focus has been the genetic factors that regulate daily physical activity. He is an Associate Editor of Medicine and Science in Sports and Exercise. He was a founding member of the National Exercise Clinical Trials Network and is a Fellow of the American College of Sports Medicine. Monica J. Hubal is an Associate Professor of Kinesiology at Indiana University-Purdue University Indianapolis, USA. She is also an Adjunct Associate Professor of Cellular and Integrative Physiology, a research scientist in the Diabetes Translational Research Center and is affiliated with the Indiana Center for Musculoskeletal Health at the Indiana University School of Medicine. Her research focuses on understanding the systems biology of emergent cardiometabolic disease and the mechanisms driving response to various interventions. She was a principal investigator in the Research Center for Genetic Medicine at the Children's National Medical Center. She is an Associate Editor for Medicine and Science in Sports and Exercise and Exercise and Sport Sciences Reviews and is a Fellow of the American College of Sports Medicine. Stephen M. Roth is a Professor of Kinesiology and Associate Dean at the University of Maryland in College Park, USA. He has researched the genetic aspects of exercise and sport for over 15 years. He is an author or co-author of over 90 peer-reviewed articles, book chapters, and books. He served as an Associate Editor for Medicine and Science in Sports and Exercise and Exercise and Sport Sciences Reviews. He is a Fellow of the National Academy of Kinesiology and the American College of Sports Medicine
Print version record
Subject Sports -- Physiological aspects -- Research
Exercise -- Physiological aspects -- Research
Human genetics -- Research
Athletic performance -- Physiological aspects -- Research
Sports -- physiology
Exercise -- physiology
Human Genetics
Athletic Performance -- physiology
MEDICAL -- Physiology.
SCIENCE -- Life Sciences -- Human Anatomy & Physiology.
MEDICAL -- Genetics.
SCIENCE -- Life Sciences -- Genetics & Genomics.
SPORTS & RECREATION -- General.
Exercise -- Physiological aspects -- Research
Human genetics -- Research
Humangenetik
Sportliche Leistung
Sportphysiologie
Trainingswissenschaft
Genre/Form handbooks.
Handbooks and manuals.
Guides et manuels.
Form Electronic book
Author Lightfoot, J. Timothy, editor.
Hubal, Monica J., editor.
Roth, Stephen M., 1973- editor.
ISBN 9781351380157
135138015X
9781351380164
1351380168
9781351380140
1351380141
9781315146287
1315146282
Other Titles Handbook of sport and exercise systems genetics