Ch. 1. Schizophrenic syndromes -- Ch. 2. General overview of contemporary antipsychotic medications -- Ch. 3. Effects of antipsychotic drugs on dopamine release and metabolism in the central nervous system -- Ch. 4. Antipsychotic drugs, Dopamine D2 receptors, and schizophrenia -- Ch. 5. D1 dopamine receptors, schizophrenia, and antipsychotic medications -- Ch. 6. Serotonin receptors as targets of antipsychotic medications -- Ch. 7. Role of adrenergic receptors in effects of antipsychotic medications on prefrontal cortical functions -- Ch. 8. Glutamate receptors in schizophrenia and antipsychotic drugs -- Ch. 9. The antipsychotic effects of sigma drugs -- Ch. 10. GABAergic drugs in schizophrenia -- Ch. 11. Receptor occupancy by antipsychotics -- concepts and findings -- Ch. 12. Regulation of neurotransmitter receptors by antipsychotic drugs -- Ch. 13. Modulation of cellular signaling pathways by antipsychotic drugs -- Ch. 14. The role of neurotransmitter receptors in the adversive effects of antipsychotic drugs -- Ch. 15. Future perspectives in antipsychotic drug development
Summary
This volume describes the discoveries that have helped revolutionize the understanding of schizophrenia and its treatment. The chapters cover the basic knowledge of schizophrenic syndromes and provide a general description of available anti-psychotic drugs