Title Antioxidant and redox regulation of genes / edited by Chandan K. Sen, Helmut Sies, Patrick A. Baeuerle

Published San Diego : Academic Press, ©2000

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Description 1 online resource (xxiv, 562 pages) : illustrations (some color), 1 color portrait Contents Reactive Species as Intracellular Messengers: -- L.-O. Klotz, K. Briviba, and H. Sies, Signalling by Singlet Oxygen in Biological Systems. -- D.R. Crawford, T. Suzuki, and K.J.A. Davies, Oxidant-modulated Gene Expression. -- H.H. Hassanain and P.J. Goldschmidt-Clermont, RAC, Superoxide, and Signal Transduction. -- S.K. Koliwad, A.K. Brzezinska, and S.J. Elliott, Redox Regulation of Ion Channels. -- J. Giron-Calle and H.J. Forman, Cell Ca<sup>2+</sup> in Signal Transduction: Modulation in Oxidative Stress. -- G.L. Schieven, Introduction of Protein Tyrosine Phosphorylation by Oxidative Stress and its Implications. -- A.A. Deora and H.M. Lander, Regulation of Signal Transduction and Gene Expression by Reactive Nitrogen Species. -- Redox Sensitive Molecular Processes and Cellular Responses: -- P.A. Baeuerle, Reactive Oxygen Species as Costimulatory Signals of Cytokine-Induced NFkappaB Activation Pathways. -- T. Okamoto, T. Tetsuka, and T. Kawabe, Redox Regulation of Nuclear Factor kappa B. -- C.K. Sen, Oxidants and Antioxidants in Aptosis: Role of Bcl-2. -- V. Goossens, K. De Vos, D. Vercammen, M. Steemans, K. Vancompernolle, W. Fiers, P. Vandenabeele, and J. Grooten, Role of Reactive Oxygen Species in TNF Toxicity. -- S. Roy, C.K. Sen, A. Gozin, V. Andrieu, and C. Pasquier, Redox Regulation of Cell Adhesion Processes. -- H. Masutani, M. Ueno, S. Ueda, and J. Yodoi, Role of Thioredoxin and Redox Regulation in Oxidative Stress Response and Signalling. -- A.H. Schönthal, S. Mueller, and E. Cadenas, Redox Regulation of p21, Role of Reactive Oxygen and Nitrogen Species in Cell Cycle Progression. -- Clinical Implications of Redox Signaling and Antioxidant Therapy: -- H. Viita and S. Yl̃-Hertuala, Effect of Lipoxygenases on Gene Expression in Mammalian Cells. -- A. Azzi, Tocopherol in the Pathogenesis of Atherosclerosis: One Molecule, Several Functions. -- D.-Y. Jin and K.-T. Jeang, Peroxiredoxins in Cell Signaling and HIV Infection. -- J.S. Bertram, T. King, L. Fukishima, and F. Khachik, Enhanced Activity of an Oxidation Product of Lycopene Found in Tomato Products and Human Serum Relevant to Cancer Prevention. -- C. Bladier, J.B. de Haan, and I. Kola, Antioxidant Genes and Reactive Oxygen Species in Down's Syndrome. -- B.S. Kristal and B.P. Yu, Oxidant-mediated Repression of mtDNA Transcription. -- Y. Kajimoto, Y. Yamasaki, T. Matsuoka, H. Kaneto, and M. Hori, Suppression of the Insulin Gene Promoter Activity by Oxidative Stress. -- N. Maulik and D.K. Das, Redox Regulation of Ischemic Adaptation. -- W.C. Orr and R.S. Sohal, Oxidative Stress as a Governing Factor in Physiological Aging. -- W. Dröge, V. Hack, R. Breitkreutz, E. Holm, S. Holm, and R. Kinscherf, Antioxidants in Senescence and Wasting. -- Subject Index Signaling by singlet oxygen in biological systems / Lars-Oliver Klotz, Karlis Briviba, and Helmut Sies -- Redox regulation of gene expression / Dana R. Crawford, Toshihide Suzuki, and Kelvin J.A. Davies -- Rac, superoxide, and signal transduction / Hamdy H. Hassanain and Pascal J. Goldschmidt-Clermont -- Redox regulation of ion channels / Suneil K. Koliwad, Anna K. Brzezinska, and Stephen J. Elliot -- Cell Ca² in signal transduction : modulation in oxidative stress / Julio Girón-Calle and Henry Jay Forman -- Induction of protein tyrosine phosphorylation by oxidative stress and its implications / Gary L. Schieven -- Regulation of signal transduction and gene expression by reactive nitrogen species / Ami A. Deora and Harry M. Lander -- Reactive oxygen species as costimulatory signals of cytokine-induced NF-[kappa]B activation pathways / Patrick A. Baeuerle -- Redox regulation of NF-[kappa]B / Takashi Okamoto [and others] -- Oxidants and antioxidants in apoptosis : role of Bcl-2 / Chandan K. Sen -- Role of reactive oxygen species in tumor necrosis factor toxicity / Vera Goossens [and others] -- Redox regulation of cell adhesion processes / Sashwati Roy [and others] -- Role of thioredoxin and redox regulation in oxidative stress response and signaling / Hiroshi Masutani [and others] -- Redox regulation of p21, role of reactive oxygen and nitrogen species in cell cycle progression / Axel H. Schönthal, Sebastian Mueller, and Enrique Cadenas -- Effects of lipoxygenases on gene expression in mammalian cells / Helena Vitta and Seppo Ylä-Herttuala -- [alpha]-tocopherol in the pathogenesis of atherosclerosis : one molecule, several functions / Angelo Azzi -- Peroxiredoxins in cell signaling and HIV infection / Dong-Yan Jin and Kaun-The Jeang -- Enhanced activity of an oxidation product of lycopene found in tomato products and human serum relevant to cancer prevention / John S. Bertram [and others] Antioxidant genes and reactive oxygen species in Down's syndrome / Cécile Bladier, Judy B. de Haan, and Ismail Kola -- Oxidant-mediated repression of mitochondrial DNA transcription / Bruce S. Kristal and Byung P. Yu -- Suppression of insulin gene promoter activity by oxidative stress / Yoshitaka Kajimoto [and others] -- Redox regulation of ischemic adaptation / Nilanjana Maulik and Dipak K. Das -- Oxidative stress as a governing factor in physiological aging / William C. Orr and Rajindar S. Sohal -- Antioxidants in senescence and wasting / Wulf Dröge [and others] Summary This volume addresses oxidant-reduction or redox and antioxidant sensitive molecular mechanisms and how they are implicated in different disease processes. Possible strategies to pharmacologically and/or nutritionally manipulate such redox-sensitive molecular responses are emphasized. Key features: reactive species as intracellular messengers; redox regulation of cellular responses; and clinical implications of redox signaling and antioxidant therapy Analysis antioxidanten antioxidants redoxreacties redox reactions genexpressie gene expression oxidatieve fosforylering oxidative phosphorylation oxidatiemiddelen oxidants celbiologie cellular biology veroudering senescence verouderen aging genregulatie gene regulation oxidatieve stress oxidative stress Molecular Biology (General) Cellular Biology Moleculaire biologie (algemeen) Celbiologie Bibliography Includes bibliographical references and index Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL Print version record digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL Subject Active oxygen in the body. Genetic regulation. Cellular signal transduction. Antioxidants -- Physiological effect Active oxygen -- Pathophysiology Antioxidants. Oxidation-reduction reaction. Gene Expression Regulation -- physiology Gene Expression Regulation Signal Transduction Antioxidants Oxidation-Reduction Oxygen -- physiology antioxidant. MEDICAL -- Biochemistry. Oxidation-reduction reaction Antioxidants Active oxygen in the body Active oxygen -- Pathophysiology Antioxidants -- Physiological effect Cellular signal transduction Genetic regulation Form Electronic book Author Sen, Chandan K. Sies, H. (Helmut), 1942- Baeuerle, P. A. (Patrick Alexander), 1957- ISBN 9780126366709 0126366705 9780080527291 0080527299 1281033626 9781281033628

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