Description |
1 online resource (xvi, 617 pages) : illustrations (some color) |
Series |
Cancer drug discovery and development |
|
Cancer drug discovery and development.
|
Contents |
Front Matter; The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumors; Influence of Tumor pH on Therapeutic Response; Tumor Oxygenation and Treatment Response; Oncogenes and Tumor Suppressor Genes in Therapeutic Resistance; PET Imaging of Response and Resistance to Cancer Therapy; Cancer Stem Cells Implications for Development of More Effective Therapies; Therapeutic Resistance in Leukemia; Tumor Site Implantation and Animal Model Selection in Oncology; In Vivo Resistance; Characteristics of the Metastatic Phenotype; The Microenvironment and Drug Resistance |
Summary |
Helps in understanding the complex interactions between host, tumor and cytotoxic or immunomodulatory agents. This work addresses the resistance of solid tumors to anticancer therapeutics by considering mechanisms that involve alterations in genetics and epigenetics, cellular biochemistry, and properties related to physiology of solid tumor mass |
Bibliography |
Includes bibliographical references and index |
Notes |
English |
In |
Springer e-books |
Subject |
Drug resistance in cancer cells.
|
|
Drug Resistance, Neoplasm
|
|
Antineoplastic Agents -- therapeutic use
|
|
MEDICAL -- Oncology.
|
|
HEALTH & FITNESS -- Diseases -- Cancer.
|
|
Drug Resistance, Neoplasm.
|
|
Antineoplastic Agents -- therapeutic use.
|
|
Cellules cancéreuses -- Résistance aux médicaments.
|
|
Drug resistance in cancer cells.
|
|
Drug resistance in cancer cells
|
Form |
Electronic book
|
Author |
Teicher, Beverly A., 1952-
|
ISBN |
1588295303 |
|
1597450359 |
|
9781597450355 |
|
9781588295309 |
|