Description |
1 online resource (160 pages) : illustrations (some color) |
Series |
Medical intelligence unit |
|
Medical intelligence unit (Unnumbered : 2003)
|
Contents |
FasL and Fas: typical members of the TNF ligand and receptor family / Anja Krippner-Heidenreich and Peter Scheurich -- FasL-independent activation of Fas / Faustino Mollinedo and Consuelo Gajate -- Role of ceramide in CD95 signaling / Volker Teichgräber, Gabriele Hessler and Erich Gulbins -- Regulation of Fas signaling by FLIP proteins / Margot Thome -- Fas-induced necrosis / Tom Vanden Berghe [and others] -- Fas -- more than an apoptosis inducer / Harald Wajant -- Retrograde Fas ligand signaling -- FasL and Fas in liver homeostasis and hepatic injuries -- Fas-activation, development and homeostasis of T cells / Georg Häcker -- The FasL-Fas system in disease and therapy -- Tools for activation and neutralization of Fas signaling |
Summary |
Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph. D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule |
Bibliography |
Includes bibliographical references and index |
In |
Springer e-books |
Subject |
CD antigens.
|
|
Cellular signal transduction.
|
|
Glycoproteins.
|
|
fas Receptor
|
|
Adaptor Proteins, Signal Transducing
|
|
Membrane Glycoproteins
|
|
Antigens, CD
|
|
Signal Transduction
|
|
SCIENCE -- Life Sciences -- Anatomy & Physiology.
|
|
Antigens, CD95.
|
|
Adaptor Proteins, Signal Transducing.
|
|
Membrane Glycoproteins.
|
|
CD antigens.
|
|
Cellular signal transduction.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Glycoproteins
|
|
CD antigens
|
|
Cellular signal transduction
|
Form |
Electronic book
|
Author |
Wajant, Harald.
|
ISBN |
0387321721 |
|
9780387321721 |
|
9780387345734 |
|
0387345736 |
|
6610816239 |
|
9786610816231 |
|