Limit search to available items
Book Cover

Title Fas signaling / [edited by] Harald Wajant
Published Georgetown, Tex. : Landes Bioscience/ ; New York, N.Y. : Springer Science+Business Media, ©2006


Description 1 online resource (160 pages) : illustrations (some color)
Series Medical intelligence unit
Medical intelligence unit (Unnumbered : 2003)
Contents FasL and Fas: typical members of the TNF ligand and receptor family / Anja Krippner-Heidenreich and Peter Scheurich -- FasL-independent activation of Fas / Faustino Mollinedo and Consuelo Gajate -- Role of ceramide in CD95 signaling / Volker Teichgräber, Gabriele Hessler and Erich Gulbins -- Regulation of Fas signaling by FLIP proteins / Margot Thome -- Fas-induced necrosis / Tom Vanden Berghe [and others] -- Fas -- more than an apoptosis inducer / Harald Wajant -- Retrograde Fas ligand signaling -- FasL and Fas in liver homeostasis and hepatic injuries -- Fas-activation, development and homeostasis of T cells / Georg Häcker -- The FasL-Fas system in disease and therapy -- Tools for activation and neutralization of Fas signaling
Summary Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph. D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule
Bibliography Includes bibliographical references and index
In Springer e-books
Subject CD antigens.
Cellular signal transduction.
fas Receptor
Adaptor Proteins, Signal Transducing
Membrane Glycoproteins
Antigens, CD
Signal Transduction
SCIENCE -- Life Sciences -- Anatomy & Physiology.
Antigens, CD95.
Adaptor Proteins, Signal Transducing.
Membrane Glycoproteins.
CD antigens.
Cellular signal transduction.
Sciences de la vie.
CD antigens
Cellular signal transduction
Form Electronic book
Author Wajant, Harald.
ISBN 0387321721