| Description |
1 online resource (xxv, 288 pages) : illustrations (some color) |
| Contents |
Mechanics of antigen processing. Class I MHC antigen processing / Peter J. Miller and Edward J. Collins -- The mechanics of class II processing: establichment of a peptide class II hierarchy / James R. Drake and Andrea J. Sant -- The phenomenon of immunodomination: speculations on the nature of immunodominance / Alessandro Sette and Roshni Sundaram -- Proteosome specificity and immuno-proteosomes. Endogenous antigen processing / Jonathan W. Yewdell -- Effect of the T-cell repertoire on dominance. Regulation of early T-cell development in the thymus / Thomas M. Schmitt and Juan Carlos Zúñiga-Pflücker -- CD8 T-cell immunodominance, repertoire, and memory / Dalia E. Gaddis, Michael J. Fuller, and Allan J. Zajac -- Effects of pathogens on the immune response. Listeria monocytogenes infection and the CD8' T-cell hierarchy / Brandon B. Porter and John T. Harty -- Immunodominance in tuberculosis / david M. Lewinsohn and JoAnne L. Flynn -- T-cell specificity and respiratory virus infections / Sherry R. Crowe and David L. Woodland -- Effects of pathogens on the immune response: HIV / Masafumi Takiguchi -- The effects of pathogens on the immune system: viral hepatitis / Mala Maini and Antonio Bertoletti -- Immunodominance in the T-cell response to herpesviruses / Michael W. Munks and Ann B. Hill |
| Summary |
This very first handbook on the topic summarizes the current concepts and brings together in one volume the critical arguments concerning the mechanisms relevant to immunodominance. In invited chapters written by the leaders in the field, the mechanisms whereby the immune system chooses the parts of a recognized pathogen in order to start the immune response are explained and the variety of biologic processes are identified that contribute to that choice. From the contents:. * Mechanics of antigen processing. * Proteosome specificity and immuno-proteosomes. * Effect of the T cell repertoire on |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Antigens.
|
|
Immune response -- Regulation.
|
|
Immunoglobulins.
|
|
Antibody Formation -- physiology.
|
|
Antigen Presentation -- physiology.
|
|
Immune System -- physiology.
|
| Form |
Electronic book
|
| Author |
Frelinger, Jeffrey A.
|
|
John Wiley & Sons.
|
| ISBN |
3527312749 (print edition) |
|
3527607374 (electronic bk.) |
|
3527608028 (electronic bk.) |
|
9783527312740 (print edition) |
|
9783527607372 (electronic bk.) |
|
9783527608027 (electronic bk.) |
|
