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Title Inflammation in the pathogenesis of chronic diseases : the COX-2 controversy / edited by Randall E. Harris
Published New York : Springer, ©2007


Description 1 online resource (xiii, 323 pages) : illustrations
Series Subcellular biochemistry ; v. 42
Sub-cellular biochemistry ; v. 42.
Contents Historical perspectives. Anti-inflammatory drugs in the 21st century / K.D. Rainsford -- Inflammatory mechanisms of pathogenesis. Nitric oxide synthase and cyclooxygenase interactions in cartilage and meniscus: relationships to joint physiology, arthritis, and tissue repair / J. Brice Weinberg, Beverley Fermor, Farshid Guilak -- Obesity, inflammation, and vascular disease: the role of the adipose tissue as an endocrine organ / Paolo Calabro', Edward T.H. Yeh -- Cyclooxygenase-2 (COX-2) and the inflammogenesis of cancer / Randall E. Harris -- Role of COX-2 in inflammatory and degenerative brain diseases / Luisa Minghetti -- Inflammation and Cardiovascular Disease: the Coxib Controversy. Cardiovascular effects of the selective cyclooxygenase-2 inhibitors / William B. White -- COX-2 inhibitors and Cardiovascular Risk / Daniel J. Salzberg, Matthew R. Weir -- A biological rationale for cardiotoxic effects of rofecoxib: comparative analysis with other COX-2 selective agents and NSAIDs / R. Preston Mason [and others] -- COX-2 Blockade in cancer prevention and therapy. Cancer chemoprevention by COX-2 blockade: results of case control studies / Randall E. Harris, Joanne Beebe-Donk, Galal A. Alshafie -- Strategies for colon cancer prevention: combination of chemopreventive agents / Bandaru S. Reddy -- Inflammation and neurodegenerative disease. NSAIDs for the chemoprevention of Alzheimer's disease / Christine A. Szekely, Terrence Town, Peter P. Zandi -- Inflammation in Parkinson's disease: causative or epiphenomenal? / Andreas Hald, Johan van Beek, and Julie Lotharius -- Nutrition, inflammation and chronic disease. Essential polyunsaturated fatty acids, inflammation, atherosclerosis and cardiovascular dieseases / Michel de Logeril -- Nutritional interventiion in brain aging: reducing the effects of inflaammation and oxidative stress / Frances C. Lau, Barbara Shukitt-Hale, James Joseph
Summary Discusses the role of inflammation in the pathogenesis of major chronic diseases and the controversy regarding risk versus benefit of selective cyclooxygenase-2 (COX-2) inhibitors. This volume is intended for scientists in medicine, epidemiology, pharmacology, molecular biology, and related fields
Analysis neoplasms
digestive system
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cyclooxygenase 2 -- Inhibitors.
Nonsteroidal anti-inflammatory agents.
Inflammation -- Mediators.
Cyclooxygenase 2 Inhibitors
Inflammation -- drug therapy
Chronic Disease -- prevention & control
Pathologic Processes
Anti-Inflammatory Agents, Non-Steroidal
Inflammation Mediators
MEDICAL -- Evidence-Based Medicine.
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Diseases.
MEDICAL -- Internal Medicine.
MEDICAL -- Clinical Medicine.
Sciences de la vie.
Cyclooxygenase 2 -- Inhibitors.
Inflammation -- Mediators.
Nonsteroidal anti-inflammatory agents.
Form Electronic book
Author Harris, Randall E.
ISBN 9781402056888