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E-book

Title Angiogenesis inhibition / Rüdiger Liersch, Wolfgang E. Berdel, Torsten Kessler (eds.)
Published Berlin ; London : Springer, ©2010

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Description 1 online resource (xiv, 231 pages) : illustrations
Series Recent results in cancer research, 0080-0015 ; 180
Recent results in cancer research ; 180.
Contents Angiopoietins / Yvonne Reiss -- HIF-1 alpha and cancer therapy / Mei Yee Koh, Tally R. Spivak-Kroizman, Garth Powis -- Chemokines / Andreas Hippe, Bernhard Homey, Anja Meuller-Homey -- Angiogenesis inhibition in cancer therapy / Iris Appelmann [and others] -- Vascular integrins : therapeutic and imaging targets of tumor angiogenesis / Curzio Ruegg, Gian Carlo Alghisi -- PDGF and vessel maturation / Carina Hellberg, Arne Ostman, C.-H. Heldin -- Lymphangiogenesis in cancer : current perspectives / Rudiger Liersch [and others] -- Compounds in clinical phase III and beyond / Torsten Kessler [and others] -- Metronomic chemotherapy : principles and lessons learned from applications in the treatment of metastatic prostate cancer / Urban Emmenegger [and others] -- Targeting inflammatory cells to improve anti-VEGF therapies in oncology / Hans-Peter Gerber, Ezogelin Olazoglu, Iqbal S. Gerwal -- Antibody-based vascular tumor targeting / Christoph Schliemann, Dario Neri -- Caveolae and cancer / Kerri A. Massey, Jan E. Schnitzer
Summary Angiogenesis is attracting increased scientific and clinical interest. The identification of novel mediators and targeting molecules has led to significant progress in our understanding of tumor angiogenesis and tumor vessel targeting. Important advances in cancer treatment have already emerged, and in the future, blood vessel targeting will play a significant role within individualized therapeutic strategies. This volume provides a general overview of the latest developments in angiogenesis inhibition in cancer. All aspects from the bench to the bedside are considered, with detailed attention both to basic research and to its translation into clinical practice. Individual chapters are devoted to the roles of angiopoietins, HIF-1a, chemokines, PDGF and VEGF, and vascular integrins. The latest results of clinical trials on therapeutic compounds are presented, and various advanced targeting strategies are discussed. This book will be invaluable to all who wish to learn of the most recent advances in research and treatment in this exciting field
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Neovascularization inhibitors.
Neovascularization.
Neovascularization, Pathologic
Neoplasms -- drug therapy
Neovascularization, Pathologic -- drug therapy
Angiogenesis Inhibitors
MEDICAL -- Oncology.
HEALTH & FITNESS -- Diseases -- Cancer.
Médecine.
Neovascularization
Neovascularization inhibitors
Tumorwachstum
Angiogenese
Inhibition
Form Electronic book
Author Leirsch, Rüdiger
Berdel, Wolfgang E.
Kessler, Torsten.
ISBN 9783540782810
3540782818
1282828142
9781282828148
9786612828140
6612828145