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E-book

Title Water and biomolecules : physical chemistry of life phenomena / Kunihiro Kuwajima [and others] (editors)
Published Berlin ; Heidelberg : Springer, ©2009

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Description 1 online resource
Series Biological and medical physics, biomedical engineering
Biological and medical physics, biomedical engineering.
Contents 1. Mapping Protein Folding Landscapes by NMR Relaxation -- 2. Experimental and Simulation Studies on the Folding/Unfolding of Goat a-Lactalbumin -- 3. Transition in the Higher-order Structure of DNA in Aqueous Solution -- 4. Generalized-Ensemble Algorithms for Studying Protein Folding -- 5. Protein Folding and Binding: Effective Potentials, Replica Exchange Simulations, and Network Models -- 6. Functional Unfolded Proteins: How, When, Where and Why? -- 7. Structure of the Photointermediate of Photoactive Yellow Protein and the Propagation Mechanism of Structural Change -- 8. Time-resolved Detection of Intermolecular Interaction of Photosensor Proteins -- 9. Volumetric Properties of Proteins and the Role of Solvent in Conformational Dynamics -- 10. A Statistical Mechanics Theory of Molecular Recognition -- 11. Computational Studies of Protein Dynamics -- 12. Biological Functions of Trehalose as a Substitute for Water -- 13. Life on the Edge: The Origins and Proliferation of Protein Misfolding Diseases -- 14. Effect of Light on Amyloidogenic Proteins: Nucleation and Fibril Extension -- 15. Real-time Observation of Amyloid Fibril Growth by Total Internal Reflection Fluorescence Microscopy
Summary Life is produced by the interplay of water and biomolecules. This book deals with the physicochemical aspects of such life phenomena produced by water and biomolecules, and addresses topics including "Protein Dynamics and Functions", "Protein and DNA Folding", and "Protein Amyloidosis". All sections have been written by internationally recognized front-line researchers. The idea for this book was born at the 5th International Symposium "Water and Biomolecules", held in Nara city, Japan, in 2008
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Biomolecules.
Water -- chemistry
Protein Folding
Amyloidosis -- genetics
Neurodegenerative Diseases -- genetics
MEDICAL -- Biochemistry.
Biomolecules.
Sciences de la vie.
Biomédecine.
Biomolecules
Form Electronic book
Author Kuwajima, Kunihiro.
ISBN 9783540887874
3540887873
3540887865
9783540887867