Title Alzheimer's disease and infectious causes the theory and evidence Elaine A. Moore

Published Jefferson, North Carolina McFarland & Company, Inc., Publishers [2020]

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Description 1 online resource illustrations Series McFarland health topics McFarland health topics. Contents One. The Mystery of the Mind and Consciousness -- Two. Infection as a Primary Cause -- Three. Microorganisms and the Microbiome -- Four. The Immune System, Neurodegeneration and the ­Blood-Brain Barrier -- Five. Stages and Pathology of the Disease -- Six. Herpes Viruses -- Seven. Other Associated Viruses and the Prion Connection -- Eight. Bacterial Infections -- Nine. Fungal and Protozoan Infections -- Ten. Risk Factors -- Eleven. Genetic Influences -- Twelve. Risk Reduction and Therapies -- Bibliography -- Index Summary "With the recent discovery that amyloid beta protein, the cause of plaques in Alzheimer's disease, is an antimicrobial peptide produced in response to infection, many researchers are focusing on the role infection plays in the development of Alzheimer's disease. Brain studies have also identified a number of different viruses, bacteria, fungi, and protozoa in the postmortem brain specimens of Alzheimer's patients. Infection (particularly chronic, latent and persistent infections) causes an immune response that leads to inflammation and brain cell degeneration, which are characteristic features of Alzheimer's disease. Sources of infection in Alzheimer's disease vary from childhood infections to gut microbes that find their way into the brain as a result of aging, leaky gut syndrome, and increased permeability of the blood brain barrier. Studies and ongoing clinical trials show that treatment of viral and bacterial infections, as well as restoring a healthy balance to the gut microbiome, can reduce disease risk and improve symptoms in patients with Alzheimer's disease. This book serves as an introduction to the human microbiome and the role that infection plays in the development of Alzheimer's disease."--Provided by publisher"-- Provided by publisher Bibliography Includes bibliographical references and index Notes Print version record Subject Alzheimer's disease -- Etiology Alzheimer's disease -- Risk factors Infection -- Complications Alzheimer Disease -- prevention & control Alzheimer Disease -- etiology Alzheimer's disease -- Etiology Infection -- Complications Form Electronic book ISBN 9781476638911 1476638918

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