| Description |
1 online resource |
| Contents |
Nature of neurons and their specialized membranes -- DHA contributes both benefits and risks to mammals -- Use it or lose it concept of brain health is linked to DHA -- Evolution and DHA : redefining the DHA principle -- DHA is king omega for maximizing mental speed -- DHA improves energy efficiency in neurons -- Wild conformational dynamics of DHA might save energy by sealing stretch-induced defects as fast as they occur in membranes -- Lipid whisker model and water-wire theory of energy uncoupling in neurons -- Neurons boost their energy state by using powerful antioxidant systems to protect their membranes against damage -- Oxygen-dependent damage (lipid peroxidation) of DHA membranes of neurons is inevitable and requires novel mechanisms for long-term protection -- Revised mitochondrial theory of aging and brain span -- Development of dual energy pacemaker theory of aging : role of the membrane -- Membranes and cancer -- Parkinson's disease -- Prion diseases -- Brain trauma-induced dementia -- Alzheimer's disease |
| Summary |
Studies with bacteria and other systems suggest that the omega-3 fatty acid DHA confers great benefits to neurons in maximizing both speed of neural impulses and energy efficiency. Unfortunately, studies also show that DHA's ease of oxidation damages membrane integrity. Exploring this duality, Neurons and the DHA Principle proposes a new model for the causes of neurodegeneration, in which DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering the premature death of neurons. The challenge of this book is to digest how DHA acts as an essential building bloc |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Docosahexaenoic acid.
|
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Neurons.
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Docosahexaenoic Acids -- metabolism
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Alzheimer Disease -- etiology
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Cell Death
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Neurons -- metabolism
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Docosahexaenoic Acids
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Neurons
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HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
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MEDICAL -- Neurology.
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Docosahexaenoic acid
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Neurons
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| Form |
Electronic book
|
| Author |
Valentine, David L.
|
| ISBN |
9781439874875 |
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1439874875 |
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1306000637 |
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9781306000635 |
|
0429105207 |
|
9780429105203 |
|
