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Book Cover

Title Molecular biology of Alzheimer's disease : genes and mechanisms involved in amyloid generation / edited by Christian Haass
Published Amsterdam, the Netherlands : Harwood Academic Publishers, ©1998


Description 1 online resource (xiii, 335 pages, 11 unnumbered pages of plates) : illustrations (some color)
Contents Book Cover; Title; Contents; Contributors; Introduction; Amyloid Morphology and Pathology of Alzheimer's Disease; The Tau Proteins in Alzheimer's Disease; Mutations in Three Genes are Associated with Early Onset Alzheimer's Disease; The Biological Activities and Function of the Amyloid Precursor Protein of Alzheimer's Disease; Proteolytic Processing of the -Amyloid Precursor Protein; Biosynthesis of APP and A: Multiple Pathways for the Generation of Intracellular A; The Cell Biology of Amyloid Precursor Protein
The Role of Amyloid -Peptide Terminating at Amino Acid 42 in Early Onset Alzheimer's DiseaseThe Biophysics of Amyloid -Protein Fibrillogenesis; The Molecular Biology of Presenilin 1; Molecular Biology of Presenilin 2; Presenilin Proteins and their Role in Development and Notch Signaling; The Processing of the Amyloid-Precursor-Protein (APP) in Presenilin-1 Deficient Neurons; Presenilins and their Role in Apoptosis; The Phosphorylation of Presenilin Proteins; APOE and its Role in Late Onset Alzheimer's Disease
Transgenic Animal Models in the Development of Therapeutic Strategies for Alzheimer's DiseasePresenilins in Transgenic Mice; Index
Summary Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, r
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Alzheimer's disease -- Genetic aspects
Alzheimer's disease -- Molecular aspects
Amyloid beta-protein precursor.
Molecular neurobiology.
Alzheimer Disease -- genetics
Amyloid beta-Protein Precursor
Amyloid beta-Peptides -- genetics
Amyloid beta-Protein Precursor -- genetics
HEALTH & FITNESS -- Diseases -- Alzheimer's & Dementia.
MEDICAL -- Neurology.
Alzheimer's disease -- Genetic aspects
Alzheimer's disease -- Molecular aspects
Amyloid beta-protein precursor
Molecular neurobiology
Form Electronic book
Author Haass, Christian
ISBN 020330361X