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E-book

Title Diabetes : perspectives in drug therapy / Mathias Schwanstecher, editor
Published Heidelberg [Germany] ; New York [N.Y.] : Springer-Verlag, ©2011

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Description 1 online resource (xiii, 408 pages) : illustrations
Series Handbook of experimental pharmacology, 0171-2004 ; v. 203
Handbook of experimental pharmacology ; v. 203.
Contents Targeting type 2 diabetes -- Dual acting and pan-PPAR activators as potential anti-diabetic therapies -- GLP-1 agonists and dipeptidyl-peptidase IV inhibitors -- Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes -- SGLT inhibitors as new therapeutic tools in the treatment of diabetes -- Inhibitors of 11[beta]-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy -- Nampt and its potential role in inflammation and type 2 diabetes -- Inhibition of ganglioside biosynthesis as a novel therapeutic approach in insulin resistance -- Overcoming insulin resistance with ciliary neurotrophic factor -- Thermogenesis and related metabolic targets in anti-diabetic therapy -- Interleukin-targeted therapy for metabolic syndrome and type 2 diabetes -- Fructose-1, 6-bisphosphatase inhibitors for reducing excessive endogenous glucose production in type 2 diabetes -- AMP-activated protein kinase and metabolic control -- Mitochondria as potential targets in antidiabetic therapy -- Research and development of glucokinase activators for diabetes therapy : theoretical and practical aspects
Summary Every 5 seconds someone somewhere is diagnosed with diabetes, and every 10 seconds someone dies of it. Even worse, worldwide incidence rates still inexorably escalate. Thus, it is pressing to envisage the extent of the diabetes problem and ensure synergistic approaches aiming in alleviation of its ghastly toll. The chapters of this book report cutting-edge research on molecular events in adiposity and type 2 diabetes, thus opening the way for innovative drug-based therapeutic strategies. It addresses all those who wish to keep in touch with recent developments in the field
Analysis farmacologie
pharmacology
toxicologie
toxicology
fysiologie
physiology
celbiologie
cellular biology
geneeskunde
medicine
biomedische wetenschappen
biomedicine
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Type 2 diabetes -- Treatment
Diabetes Mellitus, Type 2 -- drug therapy
Adiposity
Drug Discovery
HEALTH & FITNESS -- Diseases -- Diabetes.
Type 2 diabetes -- Treatment
Form Electronic book
Author Schwanstecher, Mathias, 1960-
ISBN 9783642172144
3642172148