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Title The ADAM family of proteases / edited by Nigel M. Hooper and Uwe Lendeckel
Published Dordrecht, the Netherlands : Springer, ©2005


Description 1 online resource (xiii, 344 pages) : illustrations
Series Proteases in biology and disease ; v. 4
Proteases in biology and disease ; v. 4.
Contents Introduction to the Adam family / Judith White [and others] -- Studies from Adam knockout mice / Keisuke Hoiruchi and Carl P. Blobel -- Adam8/MS2/CD156a / Jörg W. Bartsch [and others] -- Adam9 / Shoichi Ishiura -- Adam10 / Paul Saftig and Dieter Hartmann -- Adam12 / Ulla M. Wewer, Reidar Albrechtsen and Eva Engvall -- Adam13 function in development / Dominique Alfandari -- Adam17 / Joaquin Arribas and Soraya Ruiz-Paz -- Adam19 / Tiebang Kang [and others] -- Adam28 / Anne M. Fourie -- Mammalian Adams with testis-specific or -predominant expression / Chunghee Cho -- Overview of Adamts proteinases and Adamts 2 / Daniel S. Greenspan and Wei-Man Wang -- Adamts-3 and Adamts-14 / Carine Le Goff and Suneel S. Apte -- Adamts-4 and Adamts-5 / Anne-Marie Malfait, Micky Tortorella and Elizabeth Arner -- Adamts-13 / Han-Mou Tsai
Summary "The ADAM Family of Proteases" provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease. Although a few members of the ADAM (a disintegrin and metalloprotease) family have been known for some time, it is only in recent years through advances in genome sequencing that the large size of this family of zinc metalloproteases has become apparent. These proteins have multiple domains including a protease domain and a disintegrin domain. A branch of the family, called ADAMTS, also have thrombospondin-like motifs. The role of ADAMs
Analysis biochemie
life sciences
Biology (General)
Biologie (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Proteolytic enzymes.
Brain -- Pathophysiology
Brain chemistry.
ADAM Proteins -- genetics
ADAM Proteins -- physiology
Peptide Hydrolases
Brain Chemistry
HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
MEDICAL -- Neurology.
Sciences de la vie.
Brain chemistry.
Brain -- Pathophysiology.
Proteolytic enzymes.
Form Electronic book
Author Hooper, N. M
Lendeckel, Uwe
ISBN 9780387251516