| Description |
1 online resource (x, 159 pages) : illustrations (some color) |
| Contents |
Preface; Contents; Contributors; Chapter 1: Overview of Acid-Base Physiology; Introduction; Maintenance of Normal Acid-Base Homeostasis; Systemic and Renal Acid-Base Homeostasis; Organ Contributors to Systemic Acid-Base Status; References; Chapter 2: Metabolic Acidosis: Physiology, Presentation, and Diagnosis; Introduction; The Use of the Serum Anion Gap [1, 2]; Hyperchloremic Metabolic Acidosis [1, 2, 4, 5]; Metabolic Acidosis with Increased Anion Gap [1, 2, 4, 8]; Overproduction Acidosis; Anion Gap Acidosis Due to Acid Ingestion or Retention; References |
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Chapter 3: Etiologic Causes of Metabolic Acidosis I: The High Anion Gap AcidosesHigh Anion Gap Acidoses; Lactic Acidosis; Pathophysiology; Pathogenesis and Clinical Spectrum; Translational Approach; d-Lactic Acidosis; Ketoacidosis; Diabetic Ketoacidosis; Alcoholic Ketoacidosis; Drug- and Toxin-Induced Acidosis; Salicylate; The Osmolar Gap and Toxin-Induced Metabolic Acidosis; Ethylene Glycol; Methanol; Pyroglutamic Acid; Propylene Glycol; Uremia; Pathophysiological Basis of Correction of Acidosis of Chronic Kidney Failure; References |
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Chapter 4: Etiologic Causes of Metabolic Acidosis II: Normal Anion Gap AcidosesNon-Anion Gap (Hyperchloremic) Metabolic Acidoses; Disorders of Impaired Kidney Bicarbonate Reclamation: Proximal Renal Tubular Acidosis; Pathophysiology; Disorders of Impaired Net Acid Excretion with Hypokalemia: Classical Distal Renal Tubule Acidosis; Pathophysiology; Disorders of Impaired Net Acid Excretion with Hyperkalemia: Generalized Distal Nephron Dysfunction (Type 4 Renal Tubular Acidosis); Drug-Induced Kidney Tub ular Secretory Defects; Impaired Renin-Aldosterone Elaboration |
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Voltage Defect of Collecting Duct Disorders of Impaired Net Acid Excretion and Impaired Bicarbonate Reclamation with Normokalemia: Acidosis of Progressive Kidney Failure; References; Chapter 5: The Use of Bedside Urinary Parameters in the Evaluation of Metabolic Acidosis; Introduction; Urine pH; Limitations and Caveats in the Interpretation of Urine pH; Urine Bicarbonate; Urine Electrolytes and the Urine Anion Gap; Provocative Tests of Distal Acidification; Ammonium Chloride Test; Sodium-Dependent Tests of Distal H+ Secretion; Sodium Sulfate; Furosemide Test; Amiloride Test |
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Urinary PCO2 as an Index of Collecting Tubule H SecretionReferences; Chapter 6: Pathophysiologic Approach to Metabolic Acidosis; Introduction; Plasma Chloride and the Plasma Anion Gap; Acid Excretion by the Kidney in Metabolic Acidosis; Titratable Acids; Ammonium (NH4+); Citrate; Net Acid Excretion; Implications for Alkali Therapy; References; Chapter 7: Dietary Contributions to Metabolic Acidosis; Case Vignette; Question; Determinants of Blood pH (Review); Metabolism of Dietary Substrates; Effects of Dietary Substrates on Systemic Acid-Base Balance; The "Trade-Off" Hypothesis |
| Summary |
This timely volume provides an overview to the causes, effects on systems and clinical approaches of metabolic acidosis. Beginning with a basic understanding of the physiology, pathophysiology and development of this disease, subsequent chapters cover the characteristics and context of the processes that can cause it and a thorough presentation of management strategies. Recommended treatments include those carried out by the health care provider as well as the individual patient, such as dietary management. Clinicians and healthcare professionals will find the tools needed to recognize, work up and manage patients with metabolic acidosis in this practical and concise resource |
| Notes |
Includes index |
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Online resource; title from PDF title page (SpringerLink, viewed April 12, 2016) |
| Subject |
Acidosis.
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Metabolism -- Disorders -- Diagnosis
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Metabolism -- Disorders -- Treatment
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Acidosis
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Metabolism.
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Dietetics & nutrition.
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Renal medicine & nephrology.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Acidosis
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Metabolism -- Disorders -- Diagnosis
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Metabolism -- Disorders -- Treatment
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| Form |
Electronic book
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| Author |
Wesson, Donald E., editor.
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| ISBN |
9781493934638 |
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1493934635 |
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