| Description |
xxi, 374 pages : illustrations ; 25 cm |
| Series |
Oxford biology |
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MyiLibrary
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| Contents |
Part I. Introduction -- 1. Introducing evolutionary thinking for medicine / Stephen C. Stearns, Randolph M. Nesse, and David Haig -- Part II. The history and variation of human genes -- 2. Global spatial patterns of infectious diseases and human evolution / Jean-Franco̧̧is Gueǵan, Franck Prugnolle, and Fred́eŕic Thomas --3. Medically relevant variation in the human genome / Diddahally R. Govindaraju and Lynn B. Jorde -- 4. Health consequences of ecogenetic variation / Michael Bamshad and Arno G. Motulsky -- 5. Human genetic variation of medical significance / Kenneth K. Kidd and Judith R. Kidd -- Part III. Natural selection and evolutionary conflicts -- 6. Intimate relations : evolutionary conflicts of pregnancy and childhood / David Haig -- 7. How hormones mediate trade-offs in human health and disease / Richard G. Bribiescas and Peter T. Ellison -- 8. Functional significance of MHC variation in mate choice, reproductive outcome, and disease risk / Dagan A. Loisel, Susan C. Alberts, and Carole Ober -- 9. Perspectives on human health and disease from evolutionary and behavioral ecology / Beverly I. Strassmann and Ruth Mace -- |
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Part IV. Pathogens: resistance, virulence, variation and emergence -- 10. The ecology and evolution of antibiotic-resistant bacteria / Carl T. Bergstrom and Michael Feldgarden -- 11. Pathogen evolution in a vaccinated world / Andrew F. Read and Margaret J. Mackinnon -- 12. The evolution and expression of virulence / Dieter Ebert and James J. Bull -- 13. Evolutionary origins of diversity in human viruses / Paul M. Sharp, Elizabeth Bailes, and Louise V. Wain --14. The population structure of pathogenic bacteria / Daniel Dykhuizen and Awdhesh Kalia -- 15. Whole-genome analysis of pathogen evolution / Julian Parkhill -- 16. Emergence of new infectious diseases / Mark Woolhouse and Rustom Antia -- 17. Evolution of parasites / Jacob C. Koella and Paul Turner -- Part V. Noninfections and degenerative disease -- 18. Evolutionary biology as a foundation for studying aging and aging-related disease / Martin Ackermann and Scott D. Pletcher -- 19. Evolution, developmental plasticity, and metabolic disease / Christopher W. Kuzawa, et al. -- 20. Lifestyle, diet, and disease : comparative perspectives on the determinants of chronic health risks / William R. Leonard -- 21. Cancer : evolutionary origins of vulnerability / Mel Greaves -- 22. Cancer as a microevolutionary process / Natalia L. Komarova and Dominik Wodarz -- 23. The evolutionary context of human aging and degenerative disease / Steven N. Austad and Caleb E. Finch |
| Summary |
""Evolution in Health and Disease describes how evolutionary thinking gives valuable insights and fresh perspectives into human health and disease, establishing evolutionary biology as an essential complementary science for medicine. Integrating evolutionary thought into medical research and practice helps to explain the origins of many medical conditions, including diabetes, obesity, cardiovascular disease, asthma, allergies, other autoimmune diseases, and aging. It also provides life-saving insights into the evolutionary responses of pathogens to antibiotics, vaccinations, and other human interventions. Why do we grow old? How can we stay healthy as we age? The book discusses these and many other fascinating questions, as well as suggesting exciting possibilities for future treatment and research.""--Publisher's description |
| Notes |
Previous ed.: 1999 |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Electronic version is available via MyiLibrary |
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Mode of access: Internet via World Wide Web |
| Subject |
Diseases -- Causes and theories of causation.
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Human evolution.
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Medical genetics.
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Evolution, Molecular.
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Disease.
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Health.
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| Author |
Koella, Jacob C.
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Stearns, S. C. (Stephen C.), 1946-
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| LC no. |
2007033610 |
| ISBN |
0199207453 (hbk.) |
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0199207461 (paperback) |
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6611371362 (electronic bk.) |
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9780199207459 (hbk.) |
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9780199207466 (paperback) |
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