| Description |
xii, 496 pages : illustrations ; 29 cm |
| Contents |
Contents note continued: 13.Intravenous Immunoglobulin G from Human Plasma-Purification Concepts and Important Quality Criteria / Waltraud Kaar -- 14.Hyperimmune Immunoglobulin G / Christopher Sinclair -- 15.Rh (D) Immunoglobulin / Christopher Sinclair -- 16.Alpha1-Proteinase Inhibitor: The Disease, the Protein, and Commercial Production / Wytold Lebing -- 17.C1-Inhibitor / Sacha Zeerleder -- 18.Acid-Stabilized Plasmin as a Novel Direct-Acting Thrombolytic / Stephen Petteway Jr. -- 19.Reconstituted, Plasma-Derived High-Density Lipoprotein / Peter Lerch -- 20.Plant-Derived Manufacturing of Apolipoprotein AIMilano: Purification and Functional Characterization / Maurice Moloney -- 21.Transferrin / Jaakko Parkkinen -- 22.Plasminogen: Its Role in the Therapy of Ligneous Conjunctivitis / Claudia Nardini -- 23.Haptoglobin / Azubuike Okemefuna -- 24.Ceruloplasmin: Biology, Manufacture, and Clinical Use / Vladimir Vaschenko -- 25.Solvent/Detergent Plasma / Wolfgang Frenzel -- |
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Contents note continued: SECTION 3 PATHOGEN SAFETY OF PLASMA PRODUCTS -- 26.Ensuring Virus Safety of Plasma Products / Herbert Dichtelmuller -- 27.Transmissible Spongiform Encephalopathies and Plasma Products / Dorothy Scott -- SECTION 4 THE PHARMACEUTICAL ENVIRONMENT APPLIED TO PLASMA FRACTIONATION -- 28.Quality Assurance Requirements in Plasma Product Manufacture / Jens Jesse -- 29.Regulatory Activities Associated with Production and Commercialization of Plasma Protein Therapeutics / Timothy Lee -- 30.The Emerging Role of Global Medical Affairs in the Twenty-First Century / Ramin Farhood -- 31.Plasma for Fractionation / Timothy Hayes -- 32.The Pharmaceutical Manufacturing Environment / Ernst Hetzl -- SECTION 5 THE MARKET FOR PLASMA PRODUCTS AND THE ECONOMICS OF FRACTIONATION -- 33.The Economics of Plasma Fractionation / John Curling -- 34.Future Trends in the Plasma Products Market / Paolo Marcucci |
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Machine generated contents note: SECTION 1 INTRODUCTION TO PLASMA FRACTIONATION -- 1.The History and Development of the Plasma Protein Fractionation Industry / Joseph Bertolini -- SECTION 2 PLASMA PROTEINS FOR THERAPEUTIC USE -- 2.Production and Clinical Profile of Human Plasma Coagulation Factor VIII / Sami Chtourou -- 3.Production and Clinical Profile of Human Plasma-Derived Von Willebrand Factor / Michel Poulle -- 4.Factor Eight Inhibitor Bypassing Activity / Hans Peter Schwarz -- 5.Prothrombin Complex / Katharina Pock -- 6.Factor IX / Juan Ignacio Jorquera -- 7.Factor XI / Michel Poulle -- 8.Factor XIII and Factor X / Peter Feldman -- 9.Fibrinogen: Science and Biotechnology / Gerard Marx -- 10.Fibrin Glues and Bandages / Heinz Gulle -- 11.Production and Clinical Use of Plasma Antithrombin III / Andrea Morelli -- 12.Human Serum Albumin: A Multifunctional Plasma Protein / Mark Bulmer -- |
| Summary |
A comprehensive compilation on plasma protein production from the leading experts in the field, Production of Plasma Proteins for Therapeutic Use presents manufacturing, testing methods, and regulatory issues for plasma-derived therapeutics, a global US$10 billion industry. Culling material that until now have only been available in scattered forms across journals and books, the text features twenty-three detailed protein-by-protein chapters written by the major manufacturers of plasma protein products, addressing all aspects of these proteins, including biology, clinical use, manufacturing processes, and possible future improvements |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Blood proteins -- Therapeutic use.
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Proteins -- Separation.
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Blood Proteins -- therapeutic use.
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Blood Proteins -- chemical synthesis.
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Chemical Fractionation.
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| Author |
Bertolini, Joseph.
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Curling, J. M. (John M.)
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Goss, Neil.
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| LC no. |
2012020857 |
| ISBN |
9780470924310 (hbk.) |
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