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Book

Title Design of caspase inhibitors as potential clinical agents / editor(s), Tom O'Brien, Steven D. Linton
Published Boca Raton : Taylor & Francis, 2009

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Location Call no. Vol. Availability
 MELB  572.76 Obr/Doc  AVAILABLE
Description pages ; cm
Series CRC enzyme inhibitors series
CRC enzyme inhibitors series.
Contents Mammalian caspase activation pathways in apoptosis and inflammation / Susan Logue and Seamus Martin -- Role of caspases in inflammatory diseases / Kristof Kersse ... [et al.] -- Role of caspases in apoptotic-driven indications / Takashi Matsui -- Kinetics and catalytic activity of caspases / Kip Nalley -- Non-peptide small molecule inhibitors of caspases / Alexandre Ivachtchenko ... [et al.] -- Identification of inflammatory caspase inhibitors / John Wos and Thomas Demuth Jr -- Identification of apoptotic caspase inhibitors / Brett Ullman -- Discovery of a first-in-class apoptotic caspase inhibitor, emricasan (pf-03491390/idn-6556) / Niel Holgen -- Novel approaches to caspase inhibitor discovery / Justin Scheer and Michael Romanowski -- Therapeutic potential for caspase inhibitors : present and future / Hiroyuki Eda
Bibliography Includes bibliographical references and index
Subject Cysteine proteinases.
Cysteine proteinases -- Inhibitors.
Caspase Inhibitors.
Apoptosis.
Caspases -- physiology.
Caspases -- therapeutic use.
Author O'Brien, Tom.
Linton, Steven D.
LC no. 2008025506
ISBN 9781420045406 hardback alkaline paper
1420045407 hardback alkaline paper