Description |
xxii, 501 pages : illustrations (some color) ; 25 cm |
Contents |
Prologue : an overview of protein modular domains as adaptors / Tom L. Blundell -- 1. The SH2 domain : a prototype for protein interaction modules / Tony Pawson, Gerald D. Gish and Piers Nash -- 2. SH3 domains / Bruce J. Mayer and Kalle Saksela -- 3. The WW domain / Marius Sudol -- 4. EVH1/WH1 domains / Linda J. Ball, Urs Wiedemann, Jurgen Zimmermann and Thomas Jarchau -- 5. The GYF domain / Christian Freund -- 6. PTB domains / Ben Margolis and Linton M. Traub -- 7. The FHA domain / Daniel Durocher -- 8. Phosphoserine/threonine binding domains / Andrew E. H. Elia and Michael B. Yaffe -- 9. The eukaryotic protein kinase domain / Arvin C. Dar, Leanne E. Wybenga-Groot and Frank Sicheri -- 10. Structure, specificity, and mechanism of protein lysine methylation by SET domain enzymes / James H. Hurley and Raymond C. Trievel -- 11. The structure and function of the bromodomain / Kelley S. Yan and Ming-Ming Zhou -- 12. Chromo and chromo shadow domains / Joel C. Eissenberg and Sepideh Khorasanizadeh -- 13. PDZ domains : intracellular mediators of carboxy-terminal protein recognition and scaffolding / Laurence A. Lasky, Nicholas J. Skelton and Sachdev S. Sidhu -- 14. EH domains and their ligands / Brian K. Kay, Michael D. Scholle and Fred J. Stevens -- 15. Ubiquitin binding modules : the ubiquitin network beyond the proteasome / Stefano Confalonieri and Pier Paolo Di Fiore -- 16. The calponin homology (CH) domain / Mario Gimona and Steven J. Winder -- 17. PH domains / Mark A. Lemmon and David Keleti -- 18. ENTH and VHS domains / Vimal Parkash, Olli Lohi, Ismo Virtanen and Veli-Pekka Lehto -- 19. PX domains / Matthew L. Cheever and Michael Overduin -- 20. Peptide and protein repertoires for global analysis of modules / Krzysztof Bialek, Andrzej Swistowski and Ronald Frank -- 21. Computational analysis of modular protein architectures / Rune Linding, Ivica Letunic, Toby J. Gibson and Peer Bork -- 22. Nomenclature for protein modules and their cognate motifs / Pal Puntervoll and Rein Aasland -- Epilogue : new levels of complexity in the functional roles of modular protein interaction domains : switches and sockets in the circuit diagrams of cellular systems biology / Harel Weinstein |
Summary |
"The definitive reference on protein modules covers all relevant modular domains mediating protein-protein interactions. Structure, function and interaction partners of the domains are systematically treated, a general section covers methods to study protein-protein interactions on a proteome-wide scale."--BOOK JACKET |
Notes |
Formerly CIP. Uk |
Bibliography |
Includes bibliographical references and index |
Subject |
Protein-protein interactions.
|
|
Proteomics.
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Author |
Cesareni, Giovanni.
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LC no. |
2006280499 |
ISBN |
352730813X : |
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