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E-book
Author Zivin, Justin A.

Title TPA for stroke : the story of a controversial drug / Justin A. Zivin, John Galbraith Simmons
Published New York : Oxford University Press, 2011
Online access available from:
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Description 1 online resource (xiv, 191 pages)
Contents Code stroke on Market street -- Clot-buster : the natural history -- Dead or alive -- Brain-O -- The brain doctors cometh : slowly -- What emergency? -- Money and brains -- Deer in the headlights -- Call 911, 112, 15 ... even 999 -- Persistence of a most controversial drug -- Through the looking glass -- Post-script
Summary Without warning stroke can paralyze, blind, or kill. Some victims recover, but many do not and may even suffer another disabling or fatal attack. The drug known as tPA can drastically reduce the long-term disability associated with stroke, but despite its near-miraculous capabilities and the growing support of most neurologists, it has been slow to win acceptance as the standard of care in emergency departments nationwide. tPA for Stroke chronicles how this remarkable drug came to be tested in stroke victims, its early years in development by the pharmaceutical giant Genentech, and its eventua
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cerebrovascular disease -- Chemotherapy -- History.
Tissue plasminogen activator -- Therapeutic use -- History.
Stroke -- drug therapy.
Stroke -- history.
Fibrinolytic Agents -- therapeutic use.
Tissue Plasminogen Activator -- history.
Tissue Plasminogen Activator -- therapeutic use.
Genre/Form History.
Form Electronic book
Author Simmons, John, 1949-
ISBN 0199780943 (electronic bk.)
9780199780945 (electronic bk.)