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E-book

Title Integrating omics data / edited by George Tseng, Debashis Ghosh, Xianghong Jasmine Zhou
Published New York, NY : Cambridge University Press, 2015
©2015

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Description 1 online resource (x, 461 pages, 24 unnumbered pages of plates)
Contents Cover -- Half title -- Title -- Copyright -- Contents -- Contributors -- Introduction -- Part A: Horizontal Meta-Analysis -- 1. Meta-Analysis of Genome-Wide Association Studies: A Practical Guide -- 2. MetaOmics: Transcriptomic Meta-Analysis Methods for Biomarker Detection, Pathway Analysis and Other Exploratory Purposes -- 3. Integrative Analysis of Many Biological Networks to Study Gene Regulation -- 4. Network Integration of Genetically Regulated Gene Expression to Study Complex Diseases -- 5. Integrative Analysis of Multiple ChIP-X Data Sets Using Correlation Motifs -- Part B: Vertical Integrative Analysis (General Methods) -- 6. Identify Multi-Dimensional Modules from Diverse Cancer Genomics Data -- 7. A Latent Variable Approach for Integrative Clustering of Multiple Genomic Data Types -- 8. Penalized Integrative Analysis of High-Dimensional Omics Data -- 9. A Bayesian Graphical Model for Integrative Analysis of TCGA Data: BayesGraph for TCGA Integration -- 10. Bayesian Models for Flexible Integrative Analysis of Multi-Platform Genomics Data -- 11. Exploratory Methods to Integrate Multisource Data -- Part C: Vertical Integrative Analysis (Methods Specialized to Particular Data Types) -- 12. eQTL and Directed Graphical Model -- 13. MicroRNAs: Target Prediction and Involvement in Gene Regulatory Networks -- 14. Integration of Cancer Omics Data into a Whole-Cell Pathway Model for Patient-Specific Interpretation -- 15. Analyzing Combinations of Somatic Mutations in Cancer Genomes -- 16. A Mass-Action-Based Model for Gene Expression Regulation in Dynamic Systems -- 17. From Transcription Factor Binding and Histone Modification to Gene Expression: Integrative Quantitative Models -- 18. Data Integration on Noncoding RNA Studies -- 19. Drug-Pathway Association Analysis: Integration of High-Dimensional Transcriptional and Drug Sensitivity Profile
Summary Tutorial chapters by leaders in the field introduce state-of-the-art methods to handle information integration problems of omics data
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Genomics -- Statistical methods
Meta-analysis.
Genomics -- methods
SCIENCE -- Life Sciences -- Biochemistry.
Genomics -- Statistical methods
Meta-analysis
Form Electronic book
Author Tseng, George, editor.
Ghosha, Debāśisa, editor.
Zhou, Xianghong Jasmine, editor
ISBN 9781316319499
1316319490
9781107706484
1107706483
9781680158908
1680158902
1107697573
9781107697577
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9781316329535
131633287X
9781316332870
1316326195
9781316326190
1316322858
9781316322857
1316309479
9781316309476
9781316316153
1316316157