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E-book
Author Price, David J., 1957 December 20-

Title Mechanisms of cortical development / David J. Price and David J. Willshaw
Published Oxford ; New York : Oxford University Press, 2000

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Description 1 online resource (xii, 315 pages) : illustrations
Series Monographs of the Physiological Society ; 48
Monographs of the Physiological Society ; no. 48
Contents 1. Introduction -- 2. Early development of the telencephalon. 1. Mammalian embryogenesis and emergence of the forebrain. 2. A fate map of the anterior neural plate. 3. The developing telencephalon. 4. Anatomy of the developing neocortex. 5. Cell proliferation and migration in neocortical development. 6. The switch from neurogenesis to gliogenesis. 7. Cell lineage. 8. How are the fates of cortical cells determined? -- 3. Molecular regulation of early forebrain and cortical development. 1. Contributions from mouse developmental genetics. 2. Methods for manipulating the mouse genome. 3. Genes that regulate development in Drosophila have homologues in mammals. 4. Types of molecule that regulate forebrain development. 5. Inductive interactions in forebrain development. 6. Generation of regional diversity in forebrain. 7. Formal models of regional specification. 8. Regulation of size differences between major forebrain structures. 9. Molecular control of cell migration. 10. Molecular control of differentiation -- 4. Guidance of axons and innervation of cortical structures. 1. Cortical connections in the adult brain. 2. Observations on the development of cortical connections. 3. Mechanisms controlling the development of axonal connections. 4. Genetic analysis of axonal guidance in non-mammalian species. 5. Mechanisms of axonal guidance in the cortex -- 5. Map formation. 1. Introduction. 2. The development of topographically ordered maps of connections. 3. The development of topographic maps in non-cortical systems -- experimental evidence. 4. The development of topographic maps in cortical systems. 5. The development of feature maps in the visual system. 6. Models for map making. 7. Models for the development of topography. 8. Models for the development of cortical feature maps
6. Mechanisms controlling the development of cortical connections at the target. 1. Introduction. 2. Mechanisms of cell death. 3. Neurotrophic factors. 4. Regulation of cell death in the developing cortex and its connections. 5. The modification of cortical connections and circuits by activity. 6. The regulation of the dendritic growth of cortical neurons. 7. Models of dendritic growth -- 7. Functional development of the cortex. 1. Overview. 2. Receptive field properties in sensory cortex. 3. Development of receptive field properties in the visual cortex. 4. Control of receptive field development. 5. Investigation of the functional development of the cortex as a whole. 6. Acquisition of the highest levels of cortical function: development of language. 7. Effects of lesions on development of cortical function in humans
Summary Evidence from several species describes processes at each stage of the development of the cortex. This single volume integrates cellular development and structural morphology with events at the biochemical and genetic level
Bibliography Includes bibliographical references (pages 231-296) and index
Notes Print version record
Subject Cerebral cortex -- Growth
Developmental neurophysiology.
Cerebral Cortex -- physiology
Cerebral cortex -- Growth.
Developmental neurophysiology.
Neuroscience.
Human Anatomy & Physiology.
Health & Biological Sciences.
Form Electronic book
Author Willshaw, David J
ISBN 9780192624277
019262427X