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E-book
Author Wahlsten, D., author.

Title Genes, brain function, and behavior : what genes do, how they malfunction, and ways to repair damage / Douglas Wahlsten
Published London : Academic Press, an imprint of Elsevier, [2019]
©2019

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Description 1 online resource
Contents Front Cover; Genes, Brain Function, and Behavior: What Genes Do, How They Malfunction, and Ways to Repair Damage; Copyright; Contents; Author Biography; Preface; Precision Medicine and Consumer genetics: The Personal Genome; Clear Questions, Different Answers, or No Answers; Authoritative Sources; References; Acknowledgments; Chapter 1: Levels and Explanations; Levels and Scientific Disciplines; Levels and Size; Properties and Connections; Levels and Genes; Animal Models; The Experience of Pain; Expertise and Applications; Highlights; References; Chapter 2: Genes; DNA, RNA and Protein
Gene Names and Gene FunctionsMutation; Genotype and Phenotype; Sources of Information; Highlights; References; Further Reading; Chapter 3: Gene Expression; Inside and Outside the Nucleus; Gene Expression; Suppression of Gene Expression; Early Experience and Lasting Changes; Learning and Memory; Transgenerational Effects of Environment; Genes, Environment, Other; RNA Genes; Beyond Dichotomies; Heredity; A Gut Feeling About Heredity; Definitions Used in This Book; Highlights; References; Chapter 4: The Nervous System; Gross Anatomy and Art; Parts of the Brain; Neurons; Complexity
Synaptic TransmissionNeurotransmitters; Gene Expression in Brain; Sensory Input; Smell or Olfaction; Pheromones; Ligands; Taste; Touch; Nociception; Pain; Motor Output; Functions and Systems; Highlights; References; Chapter 5: Development; The Early Embryo; Rapid Transformations; Gene Expression; Extreme Phenotypic Plasticity; Emergence of the Nervous System; Early Gene Expression; Induction of Nervous System; HOX and the Head-Tail Axis; Making Connections; Axon Outgrowth and Path Finding; Synapse Formation; Plasticity of Development; Cell Death and Axon Pruning
Synaptic Competition and RefinementEarly Visual Experience and Critical Periods; Highlights; References; Chapter 6: Behavior; Kinds of Tests and Measures; The Quest for Natural Behavior; Unobtrusive Observations; Physical Measures; Self-report; Self-ratings for Preliminary Screening; Rating by a Parent or Friend; Rating by a Trained Observer; Multiple-Choice Items; Diagnosis by a Professional; Behaviors Vs Psychological Constructs; Goals of Testing and Applications of Test Scores; Standardized Psychological Tests; Choice of Test Items; Standardization; Statistical Transformation
Generate the IQ ScoreExample-Hypothetical; Changing Standards; The SAT; Tests With No Standards; Clinical Interview and Diagnosis; Comparing Systems; Agreement Between Psychiatrists; The Interview; Changing Criteria and Categories; DSM Critiques-Internal; DSM Critiques-External; Steps Toward New Diagnostic Systems; Conclusions; Highlights; References; Chapter 7: Single-Gene and Chromosomal Disorders; Alleles; Genetic Transmission; The Relation of Genotype to Phenotype: Gene Expression; Recessive Expression; Dominant Expression; Multiple Alleles, Genotypes, and Phenotypes; Instructive Examples
Summary Genes, Brain Function, and Behavior offers a concise description of the nervous system that processes sensory input and initiates motor movements. It reviews how behaviors are defined and measured, and how experts decide when a behavior is perturbed and in need of treatment. Behavioral disorders that are clearly related to a defect in a specific gene are reviewed, and the challenges of understanding complex traits such as intelligence, autism and schizophrenia that involve numerous genes and environmental factors are explored. New methods of altering genes offer hope for treating or even preventing difficulties that arise in our genes. This book explains what genes are, what they do in the nervous system, and how this impacts both brain function and behavior
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Behavior genetics.
Neurogenetics.
Nervous system.
Genetics, Behavioral
Genetic Phenomena
Brain -- physiology
Nervous System
SCIENCE -- Life Sciences -- Zoology -- General.
Nervous system
Behavior genetics
Neurogenetics
Form Electronic book
ISBN 9780128128336
012812833X