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Title Hypertension and heart failure : epidemiology, mechanisms and treatment / Maria Dorobantu, Giuseppe Mancia, Guido Grassi, Victor Voicu, editors
Published Cham, Switzerland : Springer, 2019

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Description 1 online resource (ix, 416 pages) : illustrations (some color)
Series Updates in hypertension and cardiovascular protection, 2366-4606
Updates in hypertension and cardiovascular protection, 2366-4606
Contents Intro; Preface; Contents; Part I: Epidemiological Aspects; 1: Epidemiological Aspects (Prevalence and Risk of Heart Failure Related to Blood Pressure); 1.1 Prevalence and Incidence of Heart Failure; 1.1.1 Heart Failure Definition and Classification; 1.1.2 Heart Failure Prevalence; 1.1.3 Incidence of Heart Failure; 1.1.4 Secular Trends in Heart Failure Epidemiology; 1.1.5 Heart Failure Epidemiology in Middle- and Low-Income Countries; 1.1.6 Mortality in Heart Failure; 1.2 Epidemiology of Hypertension and Heart Failure; 1.3 Conclusion; 1.4 Future Directions; References
Part II: Mechanisms of Heart Failure in Arterial Hypertension2: Genetics of Hypertension and Heart Failure; 2.1 Heritability of Hypertension and Heart Failure; 2.2 Hypertension and Heart Failure: Causation; 2.3 Genetics of Hypertension and Heart Failure; 2.4 Genetic Pathways of Hypertension and Heart Failure; 2.4.1 Sodium and Intravascular Volume; 2.4.2 Autonomic Nervous System; 2.4.3 Cardiac and Vascular Mechanisms; 2.5 Future Directions; References; 3: Blood Pressure Variability and Blood Pressure Load; 3.1 Introduction; 3.2 Mechanisms; 3.3 Methods for Assessment of BPV
3.4 Indices for Estimation of BPV3.5 Clinical Relevance of BPV; 3.6 Blood Pressure Load; 3.7 Conclusions; References; 4: Hemodynamic Mechanisms; 4.1 Introduction; 4.2 LV Deformation; 4.2.1 Changes in LV Longitudinal Strain in Response to Increased Afterload; 4.2.2 Changes in LV Radial Strain in Response to Increased Afterload; 4.3 LV Remodeling; 4.4 LV End-Diastolic Filling Pressure (Diastolic Function); 4.5 The Correlation Network of BP and LV Traits; 4.6 Assessment of LV and Arterial Elastance
4.7 Area of the Pressure-Strain Loop During Ejection as Noninvasive Index of LV Performance4.8 Conclusion; References; 5: Neural Mechanisms; 5.1 Sympathetic Nervous System Activation in Human Hypertension; 5.2 Neural Reflexes in the Pathogenesis of Hypertension; 5.3 Interaction Between the Sympathetic Nervous System and the Renin-Angiotensin System; 5.4 Brain Neural Activity in Hypertension; 5.5 Heart Failure Attributable to Hypertension; 5.6 Role of Sympathetic Nervous System Activation in Heart Failure; 5.7 Role of the Kidney in the Pathophysiology of Heart Failure
5.8 Neural Reflexes in the Pathogenesis of Heart Failure5.9 Device-Based Therapeutic Interventions; 5.10 Renal Denervation in Hypertension; 5.11 Renal Denervation in Heart Failure; 5.12 Baroreflex Activation Therapy in Hypertension; 5.13 Baroreflex Activation Therapy in Heart Failure; 5.14 Carotid Body Denervation in Hypertension; 5.15 Carotid Body Denervation in Heart Failure; 5.16 Future Directions; References; 6: Natriuretic Peptides; 6.1 Introduction; 6.2 Natriuretic Peptides in HF; 6.2.1 Diagnostic Implications; 6.2.2 Prognostic Implications
Summary This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field. -- Provided by publisher
Notes Includes index
Online resource; title from PDF title page (SpringerLink, viewed April 8, 2019)
Subject Hypertension.
Heart failure.
Hypertension
Heart Failure
Heart failure
Hypertension
Form Electronic book
Author Dorobanţu, Maria, editor.
Mancia, Giuseppe, editor.
Grassi, Guido, 1954- editor.
Voicu, Victor A., editor.
ISBN 9783319933207
3319933205
9783319933214
3319933213