| Description |
1 online resource (xvi, 316 pages) : illustrations (some color) |
| Contents |
Strategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls |
| Summary |
Since penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics |
| Notes |
Includes index |
|
Online resource; title from PDF title page (SpringerLink, viewed October 21, 2013) |
| Subject |
Anti-infective agents.
|
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Anti-Infective Agents -- pharmacology
|
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Drug Compounding
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Anti-Infective Agents
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MEDICAL -- Pharmacology.
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Anti-infective agents
|
| Form |
Electronic book
|
| Author |
Villa, Tomás G., editor
|
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Veiga-Crespo, Patricia, editor
|
| ISBN |
9783642404443 |
|
3642404448 |
|
