Reactive Oxygen Species, Synaptic Plasticity, and Memory -- Nitric Oxide Biochemistry: Pathophysiology of Nitric Oxide-Mediated Protein Modifications -- Redox Imbalance in the Endoplasmic Reticulum -- Exocytosis, Mitochondrial Injury and Oxidative Stress in Neurodegenerative Diseases -- Neuronal Vulnerability to Oxidative Damage in Aging -- Ischemia-Reperfusion Induces ROS Production from Three Distinct Sources -- Alzheimer Disease: Oxidative Stress and Compensatory Responses -- Oxidative Stress Associated Signal Transduction Cascades in Alzheimer Disease -- Nitrated Proteins in the Progression of Alzheimer's Disease: A Proteomics Comparison of Mild Cognitive Impairment and Alzheimer's Disease Brain -- Parkinson's Disease: An Overview of Pathogenesis -- Protein Oxidation Triggers the Unfolded Protein Response and Neuronal Injury in Chemically Induced Parkinson Disease -- Treating Oxidative Neural Injury: Methionine Sulfoxide Reductase Therapy for Parkinson's Disease
Summary
Examines evidence and research supporting the importance of oxidative injury in selected animal models of both neurodegenerative diseases and neural injury. This book discusses oxidative injury in a selected model, analyzing the major cellular mechanisms that underpin the progression of neural injury
