| Description |
1 online resource (xi, 281 pages) : illustrations (some color) |
| Contents |
Blood-brain barrier and roots of entry of metal ions into the brain : metal ion transport and distribution in the brain -- Metal ion-induced redox reactions, oxidative stress and possible impact on neurodegeneration -- Copper metabolism in the brain -- Lithium, a neuroprotective element -- Neurotoxicity of aluminium -- Manganese in the brain functioning -- Alzheimer's disease : which metal now? -- Prion diseases and redox active metals -- Are metals involved in Cu-Zn superoxide dismutase-related familial amyotrophic lateral sclerosis -- Parkinson's disease : any role for metals -- Chelating agents in metal neurotoxicity -- Metal complexes in the brain : imaging and diagnosis |
| Summary |
This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity. Bioinorganic chemistry has a cross disciplinary approach, applying the principles of chemistry to biological systems. Metallochemistry of Neurodegeneration: Biological, Chemical and Genetic Aspects discusses the rapidly developing area of metals in the nervous system and their role in neurodegenerative disease, such as Alzheimer's, Parkinson's and prion diseases. Written by leading experts in their fields, each chapter combines elements of genetics, biochemistry and biological inorganic chemistry in its discussion. The book highlights the differences in pathologies of neurodegenerative diseases but also discusses the mechanistic similarities. Sections include: metal ions and prion diseases; metal ions and Alzheimer disease; manganese in brain functioning; metal involvement in Parkinson disease; Cu-Zn superoxide dismutase and familial amyotrophic lateral sclerosis. This book will appeal to both chemists and biologists at the post graduate and research level |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Nervous system -- Degeneration.
|
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Chemistry, Metallurgic.
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Neurodegenerative Diseases -- physiopathology.
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Ions -- adverse effects.
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Metals -- adverse effects.
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Oxidative Stress.
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Proteins -- physiology.
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Chemistry.
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SCIENCE -- Chemistry -- Inorganic.
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Science.
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Chemistry, Metallurgic.
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Nervous system -- Degeneration.
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| Form |
Electronic book
|
| Author |
Brown, David R. (David Ronald), 1964-
|
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Valensin, Gianni, 1946-
|
| LC no. |
2006497593 |
| ISBN |
9781847555311 |
|
1847555314 |
|
