Title High density lipoproteins, dyslipidemia, and coronary heart disease / Ernst J. Schaefer, editor

Published New York : Springer, ©2010

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Description 1 online resource (xxi, 205 pages) : color illustrations Series 2010 Springer E-Books Contents Introduction to high-density lipoprotein, dyslipidemia, and coronary heart disease -- Regulation of ApoA-I gene expression and prospects to increase plasma ApoA-I and HDL levels -- High density lipoprotein particles -- The kinetics and remodeling of HDL particles: lessons from inborn errors of lipid metabolism -- HDL structure, function, and anti-inflammatory properties -- Human apolipoprotein A-I deficiency -- Human appolipoprotein A-I mutants -- ATP binding cassette A1 transporter function and Tangier disease -- The role ABCG1 in cellular cholesterol efflux: relevance to atherosclerosis and endothelial function -- In vitro studies and mass flux of cholesterol between serum and macrophages -- Genetic LCAT deficiency: molecular diagnosis, plasma lipids, and atherosclerosis -- Human cholesteryl ester transfer protein in human HDL metabolism -- The HDL receptor SR-BI -- Genetic loci influencing plasma high density lipoprotein cholesterol concentrations in humans -- Nutritional and lifestyle factors and high-density lipoprotein metabolism -- Effects of ethanol intake on high density lipoprotein metabolism in humans -- Effects of estrogen on HDL metabolism -- Effects of niacin on HDL metabolism -- Effects of statins on HDL metabolism -- Therapeutic regulation of high-density lipoprotein transport in the metabolic syndrome -- Effects of cholesterol ester transfer protein inhibition on HDL metabolism -- HDL infusion therapy -- High-density lipoproteins, dyslipidemia, and heart disease: past, present, and future Summary This innovative book focuses on HDL and its relationships to triglyceride-rich particles. As new therapies for HDL raising become available, a comprehensive understanding the role of HDL in Coronary Heart Disease is of great importance. This book is an excellent resource for educating physicians and scientists about dyslipidemia and HDL metabolism, including many exogenous substances which interact with and influence HDL. Readers will benefit from the unique visual exposition and the insights of international experts Bibliography Includes bibliographical references and index Notes Print version record In Springer eBooks Subject High density lipoproteins -- Pathophysiology Coronary heart disease -- Etiology Coronary heart disease. Blood lipoproteins -- Metabolism -- Disorders. High density lipoproteins. Coronary Disease Dyslipidemias Lipoproteins, HDL -- metabolism Lipoproteins, HDL Coronary Artery Disease MEDICAL -- Physiology. SCIENCE -- Life Sciences -- Human Anatomy & Physiology. Médecine. Blood lipoproteins -- Metabolism -- Disorders Coronary heart disease Coronary heart disease -- Etiology High density lipoproteins High density lipoproteins -- Pathophysiology medicines (material) Genre/Form dissertations. Academic theses Conference papers and proceedings Academic theses. Thèses et écrits académiques. Form Electronic book Author Schaefer, Ernst J ISBN 9781441910592 144191059X 9786612828768 6612828765

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