| Description |
1 online resource (xiv, 274 pages) : illustrations, maps |
| Series |
Ecology and evolution of infectious dieseases series |
|
Ecology and evolution of infectious diseases series.
|
| Contents |
Prologue: the pertussis problem -- Introduction to pertussis transmission and epidermiological dynamics -- Basics of pertussis pathogenesis -- The immunology of Bordetalla pertussis infection and vaccination -- Pertussis epidemiology -- Role of vaccine schedules -- Animal models -- The human immune responses to pertussis and pertussis vaccines -- Evolutionary epidemiology theory of vaccination -- Temporal patterns of Bordetella pertussis genome sequence and structural evolution -- Vaccine-driven selection and the changing molecular epidemiology of Bordetella pertussis -- Congenerics: what can be learned about pertussis from pertussis-like disease caused by other Bordetella? -- Surveillance and diagnostics -- Contrasting ecological and evolutionary signatures of whooping cough epidemiological dynamics -- Pertussis immunity and the epidemiological impact of adult transmission: statistical evidence from Sweden and Massachusetts -- Public health consequences -- Epilogue: the road ahead -- Index |
| Summary |
Pertussis, or whooping cough, is a respiratory disease caused primarily by infection with the bacterium Bordetella pertussis. It remains among the leading causes of death amongst vaccine-preventable diseases worldwide and recent years have seen its alarming re-emergence in many regions (including the U.S. and much of Europe), despite sustained high levels of vaccine coverage. The causes of the resurgence remain contentious, in part due to inherent complexities of the pathogen's biology, in part due to pronounced variation in the treatment and prevention strategies between different countries and regions, and in part due to long-standing disagreement amongst scientific researchers studying pertussis. This edited volume brings together expert knowledge from disparate fields with the overall aim of synthesizing the current understanding of this critically important, global pathogen |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from digital title page (viewed on February 27, 2019) |
| Subject |
Whooping cough.
|
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Whooping cough -- Epidemiology
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Whooping cough -- Immunology
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Whooping Cough
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Whooping cough
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| Form |
Electronic book
|
| Author |
Rohani, Pejman, editor.
|
|
Scarpino, Samuel V., editor.
|
| ISBN |
9780192539861 |
|
0192539868 |
|
9780191850011 |
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0191850012 |
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