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Book Cover
E-book

Title Experimental design and reproducibility in preclinical animal studies / José M. Sánchez Morgado, Aurora Brønstad, editors
Published Cham : Springer, [2021]
©2021

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Description 1 online resource (277 pages) : illustrations (chiefly color)
Series Laboratory animal science and medicine ; volume 1
Laboratory animal science and medicine (Springer (Firm)) ; 1
Contents An introduction to reproducibility in the context of animal research -- Rodent Genetics -- Animal and environmental factors that influence reproducibility -- Microbiology and Microbiome -- Effects of untreated pain, anesthesia and analgesia in animal experimentation -- Why do we need a statistical experiment design -- Statistical tests and Sample size calculations -- Design of experiments -- Scholarly Publishing and Scientific Reproducibility -- Systematic reviews -- Planning animal experiments
Summary This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. The book addresses advanced undergraduates, graduate students and all scientists working with animals
Bibliography Includes bibliographical references
Notes Print version record
Subject Animal experimentation.
Experimental design.
Animal Experimentation
Research Design
Animal experimentation
Experimental design
Experimentació animal.
Genre/Form Llibres electrònics.
Form Electronic book
Author Sánchez Morgado, José M., editor
Brønstad, Aurora, editor
ISBN 3030661474
9783030661472