| Description |
1 online resource (xiii, 353 pages, 2 unnumbered pages of plates) : illustrations (some color) |
| Contents |
Introduction / Frank T. Robb [and others] -- Compatible solutes of (hyper)thermophiles and their role in protein stabilization / Helena Santos [and others] -- Relationships among catalytic activity, structural flexibility, and conformational stability as deduced from the analysis of mesophilic-thermophilic enzyme pairs and protein engineering studies / Reinhard Sterner and Eike Brunner -- Membranes and transport proteins of thermophilic microorganisms / Sonja Verena Albers and Arnold J.M. Driessen -- Thermophilic protein-folding systems / Frank T. Robb and Pongpan Laksanalamai -- Physical properties of membranes composed of tetraether archaeal lipids / Parkson Lee-Gau Chong -- Glycolysis in hyperthermophiles / Peter Schönheit -- Industrial relevance of thermophiles and their enzymes / Garabed Antranikian -- Denitrification pathway enzymes of thermophiles / Simon de Vries and Imke Schröder -- DNA stability and repair / Malcolm F. White and Dennis W. Grogan |
|
Plasmids and cloning vectors for thermophilic archaea / Kenneth M. Stedman -- Genetic analysis in extremely thermophilic bacteria : an overview / Dennis W. Grogan -- Targeted gene disruption as a tool for establishing gene function in hyperthermophilic archaea / Haruyuki Atomi and Tadayuki Imanaka -- Nanobiotechnological potential of viruses of hyperthermophilic archaea / Tamara Basta and David Prangishvili -- Master keys to DNA replication, repair, and recombination from the structural biology of enzymes from thermophiles / Li Fan [and others] -- DNA replication in thermophiles / Jae-Ho Shin, Lori M. Kelman, and Zvi Kelman -- DNA-binding proteins and DNA topology / Kathleen Sandman -- Structure and evolution of the Thermus thermophilus ribosome / Steven T. Gregory and Albert E. Dalberg -- Protein phosphorylation at 80°C and above / Peter J. Kennelly -- Archaeal 20S proteasome: a simple and thermostable model system for the core particle / Joshua K. Michel and Robert M. Kelly |
| Summary |
"Thermophiles: Biology and Technology at High Temperatures presents a cogent summary of the progress made in studying these extrernophiles and speaks directly to the implications of that progress. Much is being learned from the study of thermophiles, especially our understanding of fundamental biology at the molecular level and the genetic mechanisms that permit adaptation and survival. By studying this extreme example of life, its subtle, yet exaggerated response mechanisms, and its development over the course of many short-lived generations, we may begin to understand the mechanisms in a number of diseases linked to improper protein folding, and also begin to more fully understand the ingenious design of DNA, and all that such an understanding implies regarding the health and survival of human life in a rapidly changing environment."--Jacket |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Thermophilic microorganisms.
|
|
Bacteria -- Physiology.
|
|
Adaptation (Physiology)
|
|
Microbial genetics.
|
|
Heat.
|
|
Bacterial Physiological Phenomena
|
|
Adaptation, Physiological
|
|
Archaea -- genetics
|
|
Archaea -- physiology
|
|
Bacteria -- genetics
|
|
Genetics, Microbial
|
|
Hot Temperature
|
|
heat.
|
|
SCIENCE -- Life Sciences -- Biology.
|
|
SCIENCE -- Life Sciences -- Microbiology.
|
|
Microbial genetics
|
|
Heat
|
|
Bacteria -- Physiology
|
|
Adaptation (Physiology)
|
|
Thermophilic microorganisms
|
| Form |
Electronic book
|
| Author |
Robb, F. T. (Frank T.)
|
| ISBN |
9781420008852 |
|
1420008854 |
|
9780429118418 |
|
0429118414 |
|
