Description |
1 online resource (xiii, 734 pages) : illustrations |
Contents |
Front cover; Foreword; Preface; Contents; Contributors; Molecular Imprinting- An Introduction; I. INTRODUCTION; II. WHAT IS MOLECULAR IMPRINTING?; III. IMPRINTING TERMINOLOGY; IV. APPROACHES TO MOLECULAR IMPRINTING; V. HOW TO PREPARE A MOLECULARLY IMPRINTED POLYMER; VI. BINDING EVALUATION; A. The Imprinting Effect; B. Strategy for Demonstrating a Real Imprinting Effect; VII. CONFIGURATIONS OF MOLECULARLY IMPRINTED POLYMERS; VIII. CHARACTERISTICS OF MOLECULARLY IMPRINTED POLYMERS; IX. MIPs-FOR WHAT PURPOSE?; X. CONCLUDING REMARKS; REFERENCES |
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A Brief History of the ''New Era'' of Molecular ImprintingI. INTRODUCTION; II. HOW DID THEY GET INVOLVED?; III. WHAT ARE THE MAIN PROBLEMS AND LIMITATIONS OF IMPRINTING AT THE PRESENT TIME?; IV. WHAT IMPRINTING PROJECTS ARE THEY WORKING ON AT PRESENT?; V. WHERE WILL MIPS BE APPLIED AND WHERE WILL RESEARCH GO IN THE FUTURE?; ACKNOWLEDGMENTS; REFERENCES; The Noncovalent Approach; I. INTRODUCTION; II. CONSIDERATIONS IN THE DESIGN OF NONCOVALENT IMPRINTING SYSTEMS A. Types of Interactions in Molecular Imprinting; B. Noncovalent Types of Interactions; C. Monomers and Cross-Linkers; D. Solvents |
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III. AREAS FOR IMPROVEMENT IN NONCOVALENTLY IMPRINTED POLYMERSIV. EXAMPLES OF MOLECULARLY IMPRINTED POLYMERS: TYPICAL TECHNIQUES AND RECIPES; V. PROTOCOL 1: AN IMPRINTED POLYMER SPECIFIC FOR THE DRUG THEOPHYLLINE; A. Preparation of a Theophylline MIP and the Corresponding Nonimprinted Polymer; B. Evaluating Theophylline MIP and NP with Batch-Mode Binding Assays; VI. PROTOCOL 2: ENANTIOSELECTIVE MIP FOR (R)-ISOPROTERENOL; A. Preparation of a (R)-Isoproterenol Imprinted Polymer; B. Evaluating the (R)-Isoproterenol MIP Using HPLC; VII. IMPRINTING WITH IMMOBILIZED TEMPLATES |
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VIII. ''ANTI-IDIOTYPIC IMPRINTING'' AND ''DIRECT MOLDING'': THE NEXT GENERATION OF MIPsACKNOWLEDGMENTS; REFERENCES; The Covalent and Other Stoichiometric Approaches; I. INTRODUCTION; II. AN EXAMPLE FOR IMPRINTING WITH COVALENT INTERACTIONS; III. OPTIMIZATION OF THE POLYMER STRUCTURE; IV. GENERAL ASPECTS OF THE BINDING SITE INTERACTION; V. DIFFERENT POSSIBILITIES OF COVALENT BINDING A. Boronic Acid-Containing Binding Site Functional Monomers; B. Using Azomethines, Ketals, and Sulfides for Covalent Binding; VI. EXAMPLES OF STOICHIOMETRIC NONCOVALENT INTERACTION A. General |
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B. Benzamidines and Guanidines as Binding SitesC. Imprinted Polymers with Multiple Hydrogen Bonded Templates; D. Imprinting with Polymerizable Cyclodextrins Employing Host-Guest Inclusion; E. Stoichiometric Noncovalent Interactions for the Imprinting of Ampicillin; VII. CONCLUSION; VIII. PROTOCOLS OF THE PREPARATION OF TWO TYPICAL EXAMPLES OF IMPRINTED POLYMERS A. Polymer from Scheme 2; B. Polymer from Template 14 and Binding Site 3; ACKNOWLEDGMENT; REFERENCES; The Semi-Covalent Approach; I. WHY USE A SEMI-COVALENT APPROACH?; II. SEMI-COVALENT APPROACH USING CARBOXYLIC ESTER TEMPLATES |
Summary |
Molecular Imprinting - An IntroductionA Brief History of the ""New Era"" of Molecular ImprintingThe Non-Covalent ApproachThe covalent and Other Stoichiometric ApproachesThe Semi-Covalent ApproachThe Use of Metal Coordination for Controlling the Microenvironment of Imprinted PolymersSynthesis and Selection of Functional and Structural MonomersCombinatorial Approaches to Molecular ImprintingSurface ImprintingScaffold ImprintingImprinting in Inorganic MatricesPost Modification of Imprinted PolymersMolecular Imprinting Using Hybrid Materials as Host MatricesThermodynamic Considerations and the Use |
Bibliography |
Includes bibliographical references and index |
Notes |
English |
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Print version record |
Subject |
Molecular imprinting.
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Imprinted polymers.
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Monomers.
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monomers.
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SCIENCE -- Chemistry -- Organic.
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Imprinted polymers
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Molecular imprinting
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Monomers
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Form |
Electronic book
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Author |
Yan, Mingdi, 1967-
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Ramström, Olof
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LC no. |
2005297604 |
ISBN |
1420030302 |
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9781420030303 |
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1280609923 |
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9781280609923 |
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9786610609925 |
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6610609926 |
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0429132638 |
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9780429132636 |
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