| Description |
1 online resource (xiii, 509 pages) : illustrations |
| Contents |
1. Clinical overview of uveal melanoma: introduction to tumors of the eye / J. William Harbour -- 2. Clinical overview: retinoblastoma / Jerry A. Shields and Carol L. Shields -- 3. Epidemiology of uveal melanoma: patient characteristics, risk factors, and predisposing elements / Marie Diener-West and Claudia Scala Moy -- 4. Epidemiology of retinoblastoma / James J. Augsburger -- 5. Genetics of uveal melanoma: chromosomal rearrangements and the identification of genes involved in tumorigenesis / Karen Sisley and Ian G. Rennie -- 6. Structural alterations and gene expression in the pathogenesis of uveal melanoma / Paul R. van Ginkel -- 7. A cascade of genomic changes leads to retinoblastoma / Vivette D. Brown, Helen S.L. Chan, and Brenda L. Gallie -- 8. The role of the retinoblastoma protein in health, malignancy, and the pathogenesis of retinoblastoma / Kurtis R. Van Quill and Joan M. O'Brien -- 9. Biochemical pathways: differential gene expression and cellular pathways determining tumor phenotype comparison of uveal melanocytes and uveal melanoma cells in vitro / Dan-Ning Hu and Steven A. McCormick -- 10. p53 and the molecular regulation of cell fate in retinoblastoma / Robert W. Nickells and Cassandra L. Schlamp -- 11. Immunology of uveal melanoma: adaptive antitumor immunity and the basis of immunotherapy / Jerry Y. Niederkorn -- 13. Models of uveal melanoma: characterization of transgenic mice and other animal models for melanoma / Stefan Dithmar and Hans E. Grossniklaus -- 14. Using retinoblastoma models to develop new treatment: vitamin D analogues / Daniel M. Albert, Robert W. Nickells, Soesiawati R. Darjatmoko, and Isabelle Audo -- 15. Therapy of uveal melanoma: methods and risk factors associated with treatment / Dan S. Gombos and William F. Mieler -- 16. The treatment of retinoblastoma / David H. Abramson and Amy C. Schefler -- 17. Clinical trials in uveal melanoma: patient characteristics and the treatment of intraocular tumors / Timothy G. Murray, H. Culver Boldt, Brandy Hayden, and Claudia Scala Moy -- 18. Clinical trials in retinoblastoma / Emily Y. Chew -- 19. Pathology of uveal melanoma: histological parameters and patient prognosis / Robert Folberg and Jacob Pe'er -- 20. Retinoblastoma: pathology and prognosis / Ian W. McLean -- 21. Molecular genetics of retinoblastoma / Isabelle Audo and José Sahel -- 22. Genetically engineered mouse models of retinoblastoma / Jolene J. Windle and Daniel M. Albert -- 23. Treatment of extraocular retinoblastoma / Diane Puccetti -- Index |
| Summary |
This reference deals principally with the molecular biology and genetic factors which trigger and promote the two most common ocular tumours: uveal melanoma and retinoblastoma |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Eye -- Cancer
|
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Retina -- Cancer.
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Retinoblastoma.
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Uvea -- Cancer
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Eye Neoplasms -- pathology
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Uveal Neoplasms -- pathology
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Retinoblastoma -- pathology
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Retinal Neoplasms -- pathoogy
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Angiogenesis Inhibitors -- therapeutic use
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Clinical Trials
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Retinoblastoma
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Eye Neoplasms
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Uveal Neoplasms
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MEDICAL -- Oncology.
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HEALTH & FITNESS -- Diseases -- Cancer.
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Eye -- Cancer
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Retina -- Cancer
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Retinoblastoma
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Uvea -- Cancer
|
| Form |
Electronic book
|
| Author |
Albert, Daniel M
|
|
Polans, Arthur
|
| ISBN |
0824756312 |
|
9780824756314 |
|
020391113X |
|
9780203911136 |
|
9780824740160 |
|
0824740165 |
|
