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E-book

Title Toxicology of the liver / editors, Gabriel L. Plaa, William R. Hewitt
Edition Second edition
Published Boca Raton : CRC Press, [1998]
©1998

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Description 1 online resource : illustrations
Series Target organ toxicology series
Target organ toxicology series.
Contents Cover; Half Title; Title Page; Copyright Page; Table of Contents; Contributors; Preface; Part I: Characterization of Chemical-Induced Hepatotoxicity; 1: Drug-Induced Hepatic Disease; 2: Morphologic Characteristics of Chemical-Induced Hepatotoxicity in Laboratory Rodents; 3: Chemical-Induced Hepatocarcinogenesis; Part ll: Mechanisms of Hepatotoxicity; 4: An Overview of Peroxisome Proliferation; 5: Acetaminophen-Induced Hepatotoxicity; 6: Evaluation of Chemical-Induced Oxidative Stress as a Mechanism of Hepatocyte Death; 7: Lipid Peroxidation as a Mediator of Chemical-Induced Hepatocyte Death
8: Immunologic Mediation of Chemical-Induced Hepatotoxicity9: The Role of Nonparenchymal Cells and Inflammatory Macrophages in Hepatotoxicity; Part III: Cholestasis; 10: Cholestatic Properties of Steroid Glucuronides; 11: Mechanisms Involved in Bile Acid-Induced Cholestasis; 12: Cholestasis Produced by Combinations of Manganese and Bilirubin; 13: Evaluation of Chemical-Induced Bile Duct Proliferation; Index
Summary "This second edition looks at the physiologic, biochemical, and morphologic characteristics of hepatotoxicity and includes an analysis of techniques in molecular biology and immunochemistry, among others contributing to the growth in understanding of the toxic events involved. It focuses on clinical characterization of chemical hepatotoxicity, microscopic characteristics of the mechanisms by which chemicals can produce liver injury and experimental models useful for the study of liver dysfunction."--Provided by publisher
Bibliography Includes bibliographical references and index
Notes Vendor-supplied metadata
Subject Hepatotoxicology.
Poisoning.
Liver -- drug effects
Poisoning
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Hepatotoxicology
Gastroenterology
Toxicology
Toxicologie.
Hepatotoxemie.
Lever.
Cholestase.
Form Electronic book
Author Plaa, Gabriel L., editor
Hewitt, William R., editor
ISBN 9781439810446
1439810443