| Description |
1 online resource (316 p.) |
| Series |
Confluence of Research in Biotechnology for Human Welfare Series |
|
Confluence of Research in Biotechnology for Human Welfare Series
|
| Contents |
Cover -- Half Title -- Series -- Title -- Copyright -- Table of Contents -- Preface -- Editor Biographies -- List of Contributors -- Introduction -- Chapter 1 Sequence Analysis to Decipher Protein Functions in Health and Disease -- 1.1 Introduction -- 1.2 Identification and Characteristics of Disorder in Proteins -- 1.3 Nature of IDPs -- 1.3.1 Biophysical Characters -- 1.3.2 Solubility -- 1.3.3 Phase Transition -- 1.3.4 Biomineralization -- 1.4 Evolution of IDPs -- 1.4.1 Conservation of the Amino Acid Sequence -- 1.5 Race and Species Specificity -- 1.6 Mega Roles of IDPs |
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1.6.1 Multiple Interaction Motifs -- 1.6.2 Hubs of the Signaling Network -- 1.6.3 Formation of Isoforms -- 1.7 Structural Trio Adapted by Proteins -- 1.8 Roles of IDPs in Disease Biology -- 1.9 Future Perspectives -- 1.9.1 Acknowledgements -- References -- Chapter 2 Network Pharmacology as a Potential Tool to Unlock the Treasure Trove of Pharmaceuticals in Natural Products -- 2.1 Introduction -- 2.1.1 What Is Network Pharmacology? -- 2.1.2 The Concepts of Systems Biology and Network Pharmacology -- 2.2 Databases and Tools for Network Pharmacology Research |
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2.3 Natural Products: A Treasure Trove of Potential Therapeutics? -- 2.4 Strategies of Bioactive Compound Exploration -- 2.4.1 Research Approaches and Processes in Network Pharmacology Research -- 2.5 Network Pharmacology in Natural Product Research -- 2.5.1 Construction of a Database on Natural Products and Targets -- 2.5.2 Network Construction and Visualization -- 2.6 Systems Toxicology -- 2.7 Applications and Limitations of Network Pharmacology -- 2.8 Conclusion -- References |
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Chapter 3 Drug Discovery Approaches Targeting Dengue NS2B/NS3 Protease: A Comprehensive Review on Recent Developments -- 3.1 Introduction -- 3.2 History -- 3.3 Genomic Organization and Life Cycle of DENV -- 3.4 Advances in Anti-DENV NS2B/NS3 Inhibitors -- 3.4.1 Small Molecule NS2B/NS3 Inhibitors -- 3.4.2 RNA-Based NS2B/NS3 Inhibitors -- 3.4.3 Trans-Dominant NS2B/NS3 Inhibitors -- 3.4.4 Peptide NS2B/NS3 Inhibitors -- 3.4.5 Repurposed Drugs as DENV NS2B/NS3 Inhibitors -- 3.5 Conclusion -- References -- Chapter 4 Modern Computational Tools for Vaccine Engineering -- 4.1 Introduction |
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4.1.1 Vaccines -- 4.1.2 History -- 4.1.3 Vaccine Types -- 4.2 Reverse Vaccinology for In Silico Identification of Potential Vaccine Candidates (PVCs) -- 4.3 Epitope Modeling by Immune-Informatics -- 4.3.1 Details of a Few Popular Software -- 4.3.2 Prediction of B-Cell Epitopes -- 4.3.3 Some of the Most Promising Approaches for Epitope Determination -- 4.4 Antigenicity Prediction -- 4.5 Allergenicity -- 4.6 Toxicity -- 4.7 Prediction of the Physicochemical Properties of Antigenic Protein -- 4.8 Conclusion -- References -- Chapter 5 Precision Medicine -- Scope and Significance -- 5.1 Introduction |
| Summary |
This book gives detailed overview on ""Medical Biotechnology"" along with various aspects like industrial or R&D setting to create enzymes and synthesize chemicals to use in medical applications. The book covers a wide array of topics thus providing a holistic understanding of medical biotechnology |
| Notes |
Description based upon print version of record |
|
5.2 Different Aspects of Precision Medicine |
| Genre/Form |
Electronic books
|
| Form |
Electronic book
|
| Author |
Tandon, Ritesh
|
|
Pal, Uttam
|
| ISBN |
9781040010075 |
|
1040010075 |
|
