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E-book

Title Polycystic ovary syndrome : current and emerging concepts / Lubna Pal, David B. Seifer, editors
Edition Second edition
Published Cham, Switzerland : Springer, 2022

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Description 1 online resource (1 volume) : illustrations (black and white, and color)
Contents Part I. Epidemiology of Polycystic Ovary Syndrome -- 1. Diagnostic Criteria and Epidemiology of PCOS / Alexandria M. Freeman, Heather R. Burks, and Robert A. Wild-- 2. Prevalence, Presentation, and Diagnosis of PCOS in Adolescents/ Tania S. Burgert and Emily Paprocki -- 3. Polycystic Ovarian Syndrome: A Diagnosis of Exclusion/ Mira Aubuchon -- Part II. Pathophysiology, Endocrine and Metabolic Milieus of Polycystic Ovary Syndrome -- 4. Recent Advances in the Genetics of Polycystic Ovary Syndrome/ Michelle R. Jones and Mark O. Goodarzi -- 5. The Hypothalamo-Pituitary Axis in PCOS/ Chinelo C. Okigbo, Sabrina Gill, and Janet E. Hall -- 6. Ovarian Dysfunction in Polycystic Ovary Syndrome (PCOS)/ Helen D. Mason, Nafi Dilaver, and Suman Rice -- 7. The Role of the Adrenal Glands in the Hyperandrogenism associated with the Polycystic Ovarian Syndrome/ Ruth G. Freeman -- 8. Insulin Resistance and Lipotoxicity in PCOS: Causes and Consequences/ Anne-Marie Carreau, Marie-Claude Battista, and Jean-Patrice Baillargeon -- 9. Obesity, Dysmetabolic and Proinflammatory Milieu of Polycystic Ovary Syndrome/ James J. Morong and Frank González
Part III. Management of Polycystic Ovary Syndrome -- 10. Managing PCOS in the Adolescent/ Tania S. Burgert and Emily Paprocki -- 11. Managing the PCOS-Related Symptoms of Hirsutism, Acne, and Female Pattern Hair Loss/ Trisha Shah and Harry J. Lieman -- 12. Role of Insulin-Sensitizing Drugs in PCOS Management/ Dalal Kojok, Ghina Ghazeeri, and Johnny T. Awwad -- 13. Role of Statins & Resveratrol in PCOS Management/ Anna Sokalska, Israel Ortega, and Antoni J. Duleba -- 14. Role of Lifestyle, Diet and Exercise in the Management of Polycystic Ovarian Syndrome/ Amy Plano -- Part IV. Management of Polycytic Ovary Syndrome Related Infertility -- 15. Managing PCOS-Related Infertility: Ovulation Induction, In Vitro Fertilization, and In Vitro Maturation/ Saioa Torrealday and Pasquale Patrizio -- 16. Considerations and Challenges for Pregnancy in Polycystic Ovary Syndrome/ Kerry Holliman, Ethan Wu, and Christina Shih-chi Han
Part V. The Role of Surgery in the Management of Polycystic Ovary Syndrome -- 17. Rationale and considerations for Bariatric Surgery/ Héctor F. Escobar-Morreale -- 18. Surgical Management of Polycystic Ovary Syndrome: A Contemporary Viewpoint on Place of Ovarian Surgery in PCOS Management/ Melissa Taylor-Giorlando and Lubna Pal -- Part VI. Health Risks and Burden of Polycystic Ovary Syndrome -- 19. PCOS and its Association with Mental Health/ Snigdha Alur-Gupta and Anuja Dokras -- 20. Obstructive Sleep Apnea in Polycystic Ovary Syndrome/ Yvonne Chu, Janet Hilbert, and Vahid Mohsenin -- 21. Endometrial cancer and pre-cancer in polycystic ovary syndrome/ Ellen Marcus, Kaitlin Haines, and Gregory M. Gressel -- 22. Economic Burden of Polycystic Ovary Syndrome/ Carrie Riestenberg, Anika Jagasia, and Ricardo Azziz
Part VII. Emerging Concepts in Polycystic Ovary Syndrome -- 23. The Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome/ Alice Y. Chen, David B. Seifer, and Reshef Tal -- 24. Emerging Concepts: Role of Vitamin D Deficiency in the Pathogenesis of PCOS/ Samantha Simpson, Lubna Pal, and David B. Seifer -- 25. Anti-Mullerian Hormone Signaling relevance for pathophysiology of PCOS & implications for novel therapeutic approaches to managing ovulatory dysfunction of PCOS/ Alice J. Shapiro, Vitaly Kushnir, and David B. Seifer -- 26. Newer Glucose Lowering Medications and Potential Role in Metabolic Management of PCOS/ Anika K. Anam and Silvio E. Inzucchi -- 27. Intergenerational Implications of PCOS/ Molly M. Willging, David H. Abbott, and Daniel A. Dumesic
Summary Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential "ripple effects", aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS
Notes Previous edition: 2014
Bibliography Includes index
Notes Print version record
Subject Polycystic ovary syndrome.
Polycystic Ovary Syndrome
Polycystic ovary syndrome
Form Electronic book
Author Pal, Lubna, editor.
Seifer, David B., 1955- editor.
ISBN 9783030925895
3030925897