Title Medical isotope production without highly enriched uranium / Committee on Medical Isotope Production Without Highly Enriched Uranium, Nuclear and Radiation Studies Board, Division of Earth and Life Studies, National Research Council of the National Academies

Published Washington, D.C. : National Academies Press, ©2009

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Description 1 online resource (xviii, 202 pages) Series Online access: NCBI NCBI Bookshelf Contents Background and study task -- Molybdenum-99/Technetium-99m production and use -- Molybdenum-99/Technetium-99m supply -- Molybdenum-99/Technetium-99m supply reliability -- Molybdenum-99/Technetium-99m demand -- Molybdenum-99/Technetium-99m production costs -- Conversion to LEU-based production of Molybdenum-99: technical considerations -- Conversion to LEU-based production of Molybdenum-99: regulatory considerations -- Conversion to LEU-based production of Molybdenum-99: general approaches and timing -- Conversion to LEU-based production of Molybdenum-99: prospects and feasibility Summary "This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply." Notes Title from electronic title page (viewed June 1, 2009) Bibliography Includes bibliographical references Notes Sponsored by the National Academy of Sciences and the U.S. Department of Energy DE-AM01-04PI45013 English Subject Uranium -- Isotopes. Uranium -- Isotopes -- Therapeutic use Highly enriched uranium -- Isotopes -- Therapeutic use Molybdenum -- Isotopes -- Therapeutic use Technetium -- Isotopes -- Therapeutic use Radioisotopes -- Therapeutic use. Nuclear medicine -- Standards -- United States Diagnostic imaging. Radionuclide generators. Quality control. Molybdenum -- supply & distribution Molybedenum -- isolation & purification Radioisotopes -- supply & distribution Technetium Compounds -- isolation & purification Diagnostic Imaging Radionuclide Generators Quality Control quality control. POLITICAL SCIENCE -- Public Affairs & Administration. Radionuclide generators Quality control Diagnostic imaging Radioisotopes -- Therapeutic use Technetium -- Isotopes -- Therapeutic use Uranium -- Isotopes Molybdenum 99. Technetium 99m. SUBJECT United States https://id.nlm.nih.gov/mesh/D014481 Subject United States Form Electronic book Author National Research Council (U.S.). Committee on Medical Isotope Production Without Highly Enriched Uranium. ISBN 9780309130400 0309130409 1282239244 9781282239241 9786612239243 6612239247

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